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Condition (MeSH)

Gastric Outlet Obstruction

ClinicalTrials.gov lists 84 trials for Gastric Outlet Obstruction or a narrower condition beneath it. Bristol-Myers Squibb has the most among industry and government lead sponsors, with 4.

MeSH D017219 Digestive System Diseases C06
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Phase 1 Phase 1 14 Phase 1/2 Phase 1/2 7 Phase 2 Phase 2 12 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 3 Phase 4 Phase 4 4 Not applicable Not applicable 27 Observational Observational 16 Phase 1 Phase 1 14 Phase 1/2 Phase 1/2 7 Phase 2 Phase 2 12 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 3 Phase 4 Phase 4 4 Not applicable Not applicable 27 Observational Observational 16

Trials per phase (log scale)

27 of the 84 trials are tagged with Gastric Outlet Obstruction itself; the rest are tagged with a narrower condition beneath it.

Get the Gastric Outlet Obstruction report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Gastric Outlet Obstruction trials start? (23)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 10

2002: 2 trials (Observational 1, Phase 4 1) 2003: 1 trials (Phase 3 1) 2004: 2 trials (Not applicable 1, Phase 4 1) 2006: 2 trials (Observational 1, Not applicable 1) 2007: 1 trials (Phase 3 1) 2008: 2 trials (Not applicable 1, Phase 2 1) 2009: 3 trials (Observational 1, Not applicable 1, Phase 1 1) 2010: 8 trials (Observational 2, Not applicable 3, Phase 3 1, Phase 1 2) 2011: 1 trials (Phase 1/2 1) 2013: 3 trials (Not applicable 1, Phase 4 2) 2014: 2 trials (Observational 1, Phase 1/2 1) 2015: 2 trials (Not applicable 1, Phase 2 1) 2016: 5 trials (Observational 2, Not applicable 1, Phase 2 1, Phase 1 1) 2017: 4 trials (Observational 2, Not applicable 1, Phase 2 1) 2018: 2 trials (Phase 2/3 1, Phase 1 1) 2019: 3 trials (Observational 1, Not applicable 1, Phase 2 1) 2020: 8 trials (Observational 1, Not applicable 2, Phase 1/2 3, Phase 1 2) 2021: 7 trials (Observational 3, Phase 2 2, Phase 1/2 1, Phase 1 1) 2022: 6 trials (Not applicable 4, Phase 2 1, Phase 1/2 1) 2023: 3 trials (Not applicable 1, Phase 2 1, Phase 1 1) 2024: 2 trials (Observational 1, Phase 1 1) 2025: 10 trials (Not applicable 5, Phase 2 3, Phase 1 2)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 5
2025 10
2024 2
2023 3
2022 6
2021 7
2020 8
2019 3
2018 2
2017 4

Showing 10 of 23 earlier years.

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No forecast is made for this condition: it averages 4.8 trial starts a year over the five years to September, under the 5 a year the method needs.

Prediction, not a registry value: median of 36 months from start to primary completion across 20 trials still running at the 2026-10-09 snapshot; registered median of 29 months across 40 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Gastric Outlet Obstruction trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 14
Phase 1/2 7
Phase 2 12
Phase 2/3 1
Phase 3 3
Phase 4 4
Not applicable 27
Observational 16

How many Gastric Outlet Obstruction trials are recruiting? (7)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 4
Recruiting 18
Active, not recruiting 4
Completed 30
Suspended 1

Showing 5 of 7 statuses.

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Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Gastric Outlet Obstruction trials? (6)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Bristol-Myers Squibb 4
Boston Scientific Corporation 2
Cook Group Incorporated 2
GT Metabolic Solutions, Inc. 2
Xencor, Inc. 2

Showing 5 of 6 sponsors.

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Which drugs are being tested for Gastric Outlet Obstruction? (3)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Cytoxan 3
Plamotamab 2
PREDNISOLONE 2

Interventions as named in the registry (12)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
X: Lenalidomide 4
Vincristina 3
R-CHOP Protocol 2
Cytarabine IT 2
Filgrastime (G-CSF) 2

Showing 5 of 12 interventions.

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These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Gastric Outlet Obstruction trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Abdominal pain 19 3
Bleeding 13 1
Death 11 2
Pneumonia 10 3
Pyrexia 10 2

Showing 5 of 10 adverse events.

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Which publications cover Gastric Outlet Obstruction? (79)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Endoscopic ultrasonography-guided gastroenterostomy versus uncovered duodenal metal stenting for unresectable malignant gastric outlet obstruction (DRA-GOO): a multicentre randomised controlled trial. The lancet. Gastroenterology & hepatology 2025 Yes
Endoscopic or surgical gastroenterostomy for malignant gastric outlet obstruction: a randomised trial. Gut 2025 Yes
Stomach-partitioning versus conventional gastrojejunostomy for unresectable gastric cancer with gastric outlet obstruction: A propensity score matched cohort study. American journal of surgery 2024 Yes
Endoscopic ultrasonography-guided gastroenterostomy versus uncovered duodenal metal stenting for unresectable malignant gastric outlet obstruction (DRA-GOO): a multicentre randomised controlled trial. The lancet. Gastroenterology & hepatology 2024 Yes
Prospective multicenter assessment of the impact of EUS-guided gastroenterostomy on patient quality of life in unresectable malignant gastric outlet obstruction. Gastrointestinal endoscopy 2023 Yes

Showing 5 of 79 publications.

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Sub-conditions in MeSH (1)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

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