Condition (MeSH)
Pyloric Stenosis
ClinicalTrials.gov lists 57 trials for Pyloric Stenosis or a narrower condition beneath it. Bristol-Myers Squibb has the most among industry and government lead sponsors, with 4.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials per phase
9 of the 57 trials are tagged with Pyloric Stenosis itself; the rest are tagged with a narrower condition beneath it.
When did Pyloric Stenosis trials start? (22)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 7
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 2 |
| 2025 | 7 |
| 2024 | 1 |
| 2023 | 2 |
| 2022 | 2 |
| 2021 | 5 |
| 2020 | 5 |
| 2019 | 2 |
| 2018 | 1 |
| 2017 | 4 |
Showing 10 of 22 earlier years.
No forecast is made for this condition: it averages 2.6 trial starts a year over the five years to September, under the 5 a year the method needs.
Prediction, not a registry value: median of 36 months from start to primary completion across 14 trials still running at the 2026-10-09 snapshot; registered median of 29 months across 29 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Pyloric Stenosis trials in? (7)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 14 |
| Phase 1/2 | 7 |
| Phase 2 | 12 |
| Phase 3 | 2 |
| Phase 4 | 2 |
| Not applicable | 11 |
| Observational | 9 |
How many Pyloric Stenosis trials are recruiting? (6)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 2 |
| Recruiting | 11 |
| Active, not recruiting | 3 |
| Completed | 20 |
| Terminated | 8 |
Showing 5 of 6 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Pyloric Stenosis trials? (5)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Bristol-Myers Squibb | 4 |
| Xencor, Inc. | 2 |
| Astex Pharmaceuticals, Inc. | 1 |
| BiO2 Medical | 1 |
| Bnai Zion Medical Center | 1 |
Which drugs are being tested for Pyloric Stenosis? (3)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Cytoxan | 3 |
| Plamotamab | 2 |
| PREDNISOLONE | 2 |
Interventions as named in the registry (12)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| X: Lenalidomide | 4 |
| Vincristina | 3 |
| R-CHOP Protocol | 2 |
| Cytarabine IT | 2 |
| Filgrastime (G-CSF) | 2 |
Showing 5 of 12 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Pyloric Stenosis trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Pneumonia | 10 | 3 |
| Pyrexia | 10 | 2 |
| desaturation | 10 | 1 |
| Anaemia | 9 | 2 |
| Sepsis | 9 | 4 |
Showing 5 of 10 adverse events.
Which publications cover Pyloric Stenosis? (11)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Association between duration or etiology of gastroparesis and clinical response after gastric per-oral endoscopic pyloromyotomy. | Gastrointestinal endoscopy | 2019 | Yes |
| Intraoperative Endoscopic Botox Injection During Total Esophagectomy Prevents the Need for Pyloromyotomy or Dilatation. | Journal of laparoendoscopic & advanced surgical techniques. Part A | 2016 | Yes |
| Post-Operative Impact of Nasogastric Tubes on length of stay in infants with pyloric Stenosis (POINTS): A prospective randomized controlled pilot trial. | Journal of pediatric surgery | 2015 | Yes |
| Covered versus uncovered self-expandable metallic stents for palliation of malignant pyloric obstruction in gastric cancer patients: a randomized, prospective study. | Gastrointestinal endoscopy | 2010 | Yes |
| Matched study of three methods for palliation of malignant pyloroduodenal obstruction. | The British journal of surgery | 2004 | Yes |
Showing 5 of 11 publications.
Sub-conditions in MeSH (1)
MeSH descendants one level down with at least one trial, most trials first.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence and rare-disease identity.