Organization (Industry)
Astex Pharmaceuticals
ClinicalTrials.gov lists Astex Pharmaceuticals as lead sponsor of 45 trials. It has 66 active development programs and 13 approved assets.
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Trials started per year with this organization as sponsor or collaborator, 1990 onward. The series also counts trials where the organization is a collaborator; the lead-sponsor trial count does not.
2026 is partial: 0 registered with a 2026 start date. The dashed outline is the pace from the 0 registered with a start date through September, planned starts included, not adjusted; not a forecast. No forecast is made for this organization: it averages 2.0 trial starts a year over the five years to September, under the 5 a year the method needs.
Logo Otsuka Holdings, via Wikimedia Commons, Public domain. Shown to identify the organization; it may be a registered trademark.
This page covers Astex Pharmaceuticals: 45 lead-sponsored trials and 1 legal-entity registration. Part of OTSUKA ApS.
Related companies are recorded in the same corporate group by GLEIF, ROR or a curator but are not grouped here; they are listed below with their own counts and are not included in the figures above.
Disease areas (64)
Shown in this order: most trials first (counted at this company's own legal-entity record, not the consolidated group).
| Disease area | Trials |
|---|---|
| Leukemia, Myeloid, Acute | 13 |
| Myelodysplastic Syndromes | 11 |
| Lymphoma | 9 |
| Leukemia, Lymphocytic, Chronic, B-Cell | 8 |
| Leukemia, Myelomonocytic, Chronic | 8 |
Showing 5 of 64 disease areas.
Trials by start year as sponsor or collaborator (28)
Shown in this order: most recent first. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Show the table of trials by start year as sponsor or collaborator
| Year | Trials started |
|---|---|
| 2025 | 1 |
| 2024 | 2 |
| 2023 | 1 |
| 2022 | 4 |
| 2021 | 5 |
| 2020 | 8 |
| 2019 | 4 |
| 2018 | 3 |
| 2017 | 5 |
| 2016 | 2 |
Showing 10 of 28 years.
Recruitment duration, a model prediction: none of the 45 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
Active development programs (66)
Shown in this order: max phase, then active trials.
| Drug | Disease area | Max phase | Trials |
|---|---|---|---|
| Rubitecan | Pancreatic Neoplasms | Phase 3 | 4 |
| ASTX727 | Myelodysplastic Syndromes | Phase 3 | 2 |
| ASTX727 | Leukemia, Myeloid, Acute | Phase 3 | 2 |
| Guadecitabine | Leukemia, Myeloid, Acute | Phase 3 | 2 |
| ASTX727 | Leukemia, Myelomonocytic, Chronic | Phase 3 | 2 |
Showing 5 of 66 active programs.
Approved assets (13)
Shown in this order: max phase first.
| Drug | Trials |
|---|---|
| Decitabine | 5 |
| FLUOROURACIL | 2 |
| GEMCITABINE | 2 |
| Mitomycin -C | 1 |
| CARBOPLATIN | 1 |
Showing 5 of 13 approved assets.
Sponsor delivery record (1)
Enrollment hit target: the share of this sponsor's lead-sponsored trials whose actual enrollment reached the planned enrollment. On time: the share whose actual primary completion date was no later than the planned date. Each share counts only trials where we observed an estimated figure before the actual one, and n is that number of trials. Below 5 trials the count is shown as a fraction, not a percentage.
| Enrollment | Timeline |
|---|---|
| 64% hit target (n=11) | 54% on time (n=13) |
FDA inspection record (1)
| Latest classification | Inspections |
|---|---|
| NAI | 2 |
Biomarker capability evidence (250)
Shown in this order: tier desc, then gene symbol.
| Gene | Role | Evidence |
|---|---|---|
| ABL1 | Trial collaborator | Named in trial inclusion criteria |
| ABO | Trial sponsor | Named in trial inclusion criteria |
| ALB | Trial collaborator | Named in trial inclusion criteria |
| ALB | Trial collaborator | Named in trial inclusion criteria |
| ALB | Trial sponsor | Named in trial inclusion criteria |
Showing 5 of 250 evidence rows.
Not on this page
Checked, with nothing recorded for this organization: companies grouped under this page, sec-reported annual financials, financing and grant events, fda warning letters, fda untitled letters, fda recalls, fda import refusals, manufacturing and distribution sites, climate targets, as filed, workforce and board diversity, as filed, organization relationships, and clia clinical laboratory certificates.
Counted at group level under Otsuka (Japan): journals published in, us granted patents, latest dated events, and biomarkers this organization publishes on.