Condition (MeSH)
Leukocyte-Adhesion Deficiency Syndrome
ClinicalTrials.gov lists 5 trials for Leukocyte-Adhesion Deficiency Syndrome or a narrower condition beneath it. National Institute of Allergy and Infectious Diseases (NIAID) has the most among industry and government lead sponsors, with 2.
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Trials per phase
5 of the 5 trials are tagged with Leukocyte-Adhesion Deficiency Syndrome itself; the rest are tagged with a narrower condition beneath it.
When did Leukocyte-Adhesion Deficiency Syndrome trials start? (5)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 2
- Not applicable
- Observational
Top of scale: 1
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2002 | 1 |
| 2001 | 1 |
| 2000 | 1 |
| 1999 | 1 |
| 1995 | 1 |
No forecast is made for this condition: it averages 0.0 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: none of the 5 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Leukocyte-Adhesion Deficiency Syndrome trials in? (3)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 2 | 2 |
| Not applicable | 1 |
| Observational | 2 |
How many Leukocyte-Adhesion Deficiency Syndrome trials are recruiting? (3)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Completed | 3 |
| Terminated | 1 |
| Unknown status | 1 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Leukocyte-Adhesion Deficiency Syndrome trials? (3)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| National Institute of Allergy and Infectious Diseases (NIAID) | 2 |
| Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 1 |
| National Cancer Institute (NCI) | 1 |
Which publications cover Leukocyte-Adhesion Deficiency Syndrome? (4)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Lentiviral Gene Therapy for Severe Leukocyte Adhesion Deficiency Type 1. | The New England journal of medicine | 2025 | Yes |
| Clinical and functional spectrum of RAC2-related immunodeficiency. | Blood | 2024 | Yes |
| Correction of the disease phenotype in canine leukocyte adhesion deficiency using ex vivo hematopoietic stem cell gene therapy. | Blood | 2006 | Yes |
| Mixed chimeric hematopoietic stem cell transplant reverses the disease phenotype in canine leukocyte adhesion deficiency. | Veterinary immunology and immunopathology | 2003 | Yes |
Prevalence (6)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Leukocyte adhesion deficiency | Cases families | Worldwide | Not stated | Exact | |
| Leukocyte adhesion deficiency | Point prevalence | Unknown | Worldwide | Not stated | Exact |
| Leukocyte adhesion deficiency | Point prevalence | Unknown | Worldwide | Not stated | Exact |
| Leukocyte adhesion deficiency | Cases families | Worldwide | Not stated | Exact | |
| Leukocyte adhesion deficiency | Point prevalence | <1 / 1 000 000 | Latin America | Not stated | Exact |
Showing 5 of 6 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Leukocyte adhesion deficiency | 2968 | Exact | Orphadata Science knowledge files, Product 1 |
| Leukocyte adhesion deficiency | 2968 | Exact | Orphanet Rare Disease Ontology (ORDO) |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: serious adverse events in this condition's trials and sub-conditions in mesh.
Not computed for conditions with fewer than 10 trials: drugs tested.