Condition (MeSH)
Oral Ulcer
ClinicalTrials.gov lists 52 trials for Oral Ulcer or a narrower condition beneath it.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials per phase
52 of the 52 trials are tagged with Oral Ulcer itself; the rest are tagged with a narrower condition beneath it.
When did Oral Ulcer trials start? (22)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 6
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 5 |
| 2025 | 1 |
| 2024 | 1 |
| 2023 | 6 |
| 2022 | 6 |
| 2021 | 5 |
| 2020 | 1 |
| 2019 | 4 |
| 2018 | 5 |
| 2017 | 1 |
Showing 10 of 22 earlier years.
No forecast is made for this condition: it averages 3.8 trial starts a year over the five years to September, under the 5 a year the method needs.
Prediction, not a registry value: median of 30 months from start to primary completion across 6 trials still running at the 2026-10-09 snapshot; registered median of 14 months across 33 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Oral Ulcer trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 5 |
| Phase 1/2 | 2 |
| Phase 2 | 11 |
| Phase 2/3 | 3 |
| Phase 3 | 5 |
| Phase 4 | 1 |
| Not applicable | 19 |
| Observational | 6 |
How many Oral Ulcer trials are recruiting? (6)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 2 |
| Recruiting | 6 |
| Completed | 32 |
| Terminated | 2 |
| Withdrawn | 1 |
Showing 5 of 6 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Oral Ulcer trials? (4)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Amgen | 2 |
| i+Med S.Coop. | 2 |
| E2Bio Life Sciences, LLC | 1 |
| Galera Therapeutics, Inc. | 1 |
Which drugs are being tested for Oral Ulcer? (1)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| PREDNISOLONE | 2 |
Interventions as named in the registry (14)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Apremilast IR | 2 |
| Triamcinolone Acetonide alone | 2 |
| 4% Chlorhexidine Gluconate | 2 |
| Low Level Laser Therapy | 1 |
| Cisplatin Chemotherapy | 1 |
Showing 5 of 14 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Oral Ulcer trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Dehydration | 23 | 2 |
| Febrile Neutropenia | 23 | 1 |
| Vomiting | 15 | 2 |
| Dysphagia | 12 | 2 |
| Sepsis | 11 | 2 |
Showing 5 of 10 adverse events.
Which publications cover Oral Ulcer? (57)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Evaluation of low level laser therapy and lidocaine versus chlorohexidine for the management of traumatic oral ulcers in children: a randomized controlled study. | Scientific reports | 2026 | Yes |
| Effectiveness of curcumin mouthwash in preventing traumatic ulcers in orthodontic patients. | BMC oral health | 2025 | Yes |
| Assessment of the Oral Health Impact Profile (OHIP-14) improvement of different treatments for dentin hypersensitivity in noncarious cervical lesions-a randomized clinical study. | Clinical oral investigations | 2022 | Yes |
| Tongue ulcers associated with SARS-CoV-2 infection: A case series. | Oral diseases | 2022 | Yes |
| Evaluation of diode laser versus topical corticosteroid in management of Behcet's disease-associated oral ulcers: a randomized clinical trial. | Clinical oral investigations | 2022 | Yes |
Showing 5 of 57 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.