Condition (MeSH)
HIV Wasting Syndrome
ClinicalTrials.gov lists 14 trials for HIV Wasting Syndrome or a narrower condition beneath it. National Institute of Allergy and Infectious Diseases (NIAID) has the most among industry and government lead sponsors, with 7.
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Trials per phase
14 of the 14 trials are tagged with HIV Wasting Syndrome itself; the rest are tagged with a narrower condition beneath it.
When did HIV Wasting Syndrome trials start? (8)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 2
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 2
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2004 | 1 |
| 2002 | 1 |
| 2000 | 1 |
| 1999 | 1 |
| 1998 | 2 |
| 1997 | 1 |
| 1996 | 1 |
| 1995 | 1 |
No forecast is made for this condition: it averages 0.0 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: none of the 14 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are HIV Wasting Syndrome trials in? (6)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 5 |
| Phase 3 | 1 |
| Phase 4 | 1 |
| Not applicable | 3 |
| Observational | 2 |
How many HIV Wasting Syndrome trials are recruiting? (1)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Completed | 14 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most HIV Wasting Syndrome trials? (6)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| National Institute of Allergy and Infectious Diseases (NIAID) | 7 |
| Celgene Corporation | 2 |
| National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 2 |
| EMD Serono | 1 |
| Endo USA Inc., a Keenova Therapeutics Company | 1 |
Showing 5 of 6 sponsors.
Which drugs are being tested for HIV Wasting Syndrome? (5)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| THALIDOMIDE | 2 |
| Oxandrolone | 1 |
| Dronabinol | 1 |
| Testosterone Enanthate | 1 |
| Nandrolone Decanoate | 1 |
Interventions as named in the registry (10)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Megstrol Acetate | 3 |
| Megestrol acetate oral suspension nanocrystal dispersion 115 mg/mL | 1 |
| Atazanavir + Ritonavir | 1 |
| Testosteron | 1 |
| Somatropin; Recombinant human growth hormone (r hGH) | 1 |
Showing 5 of 10 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do HIV Wasting Syndrome trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Blood cortisol abnormal | 9 | 1 |
| Adrenal insufficiency | 7 | 1 |
| Adrenal suppression | 4 | 1 |
| Cardiac failure congestive | 3 | 1 |
| Anaemia | 2 | 1 |
Showing 5 of 10 adverse events.
Which publications cover HIV Wasting Syndrome? (23)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| High Viremia and Wasting Before Antiretroviral Therapy Are Associated With Pneumonia in Early-Treated HIV-Infected Kenyan Infants. | Journal of the Pediatric Infectious Diseases Society | 2017 | Yes |
| Decreased limb muscle and increased central adiposity are associated with 5-year all-cause mortality in HIV infection. | AIDS (London, England) | 2011 | Yes |
| Role of recombinant human growth hormone in HIV-associated wasting and cachexia: pathophysiology and rationale for treatment. | Clinical therapeutics | 2007 | Yes |
| Effect of nandrolone decanoate therapy on weight and lean body mass in HIV-infected women with weight loss: a randomized, double-blind, placebo-controlled, multicenter trial. | Archives of internal medicine | 2005 | Yes |
| Supplementation with a combination of beta-hydroxy-beta-methylbutyrate (HMB), arginine, and glutamine is safe and could improve hematological parameters. | JPEN. Journal of parenteral and enteral nutrition | 2004 | Yes |
Showing 5 of 23 publications.
Prevalence (3)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| AIDS wasting syndrome | Point prevalence | 1-5 / 10 000 | Europe | Not stated | Unspecified |
| AIDS wasting syndrome | Point prevalence | 1-5 / 10 000 | Europe | Not stated | Exact |
| AIDS wasting syndrome | Point prevalence | 1-5 / 10 000 | Europe | Not stated | Exact |
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| AIDS wasting syndrome | 90081 | Exact | Orphanet Rare Disease Ontology (ORDO) |
| AIDS wasting syndrome | 90081 | Exact | Orphadata Science knowledge files, Product 1 |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: sub-conditions in mesh.