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Condition (MeSH)

Epiretinal Membrane

ClinicalTrials.gov lists 123 trials for Epiretinal Membrane or a narrower condition beneath it. Alcon Research has the most among industry and government lead sponsors, with 4.

MeSH D019773 Eye Diseases C11
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Phase 1 Phase 1 2 Phase 2 Phase 2 1 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 5 Phase 4 Phase 4 6 Not applicable Not applicable 62 Observational Observational 46 Phase 1 Phase 1 2 Phase 2 Phase 2 1 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 5 Phase 4 Phase 4 6 Not applicable Not applicable 62 Observational Observational 46

Trials per phase (log scale)

123 of the 123 trials are tagged with Epiretinal Membrane itself; the rest are tagged with a narrower condition beneath it.

Get the Epiretinal Membrane report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Epiretinal Membrane trials start? (22)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 11

2004: 2 trials (Observational 1, Not applicable 1) 2005: 4 trials (Observational 1, Not applicable 1, Phase 3 1, Phase 2 1) 2006: 3 trials (Observational 2, Not applicable 1) 2008: 5 trials (Not applicable 4, Phase 3 1) 2009: 3 trials (Observational 1, Not applicable 1, Phase 4 1) 2010: 4 trials (Observational 1, Not applicable 2, Phase 2/3 1) 2011: 4 trials (Observational 1, Not applicable 3) 2012: 5 trials (Observational 1, Not applicable 2, Phase 4 1, Phase 3 1) 2013: 7 trials (Observational 2, Not applicable 4, Phase 3 1) 2014: 6 trials (Observational 4, Not applicable 2) 2015: 7 trials (Observational 2, Not applicable 5) 2016: 6 trials (Observational 1, Not applicable 5) 2017: 6 trials (Observational 2, Not applicable 4) 2018: 10 trials (Observational 6, Not applicable 3, Phase 3 1) 2019: 7 trials (Observational 3, Not applicable 3, Phase 1 1) 2020: 7 trials (Observational 5, Not applicable 1, Phase 4 1) 2021: 11 trials (Observational 4, Not applicable 5, Phase 4 1, Phase 1 1) 2022: 5 trials (Observational 1, Not applicable 4) 2023: 3 trials (Observational 1, Not applicable 2) 2024: 9 trials (Observational 3, Not applicable 5, Phase 4 1) 2025: 3 trials (Not applicable 2, Phase 4 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 5
2025 3
2024 9
2023 3
2022 5
2021 11
2020 7
2019 7
2018 10
2017 6

Forecast of the full-year count, planned starts included, not rows of this table: about 5 trials starting in 2026 and about 4 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored. The 2026 forecast is below the 5 already registered with a 2026 start date: at the cutoff, 1 trials were already registered to start in October to December, more than the method's monthly average allows for, and the method does not use those planned starts.

Prediction, not a registry value: median of 26 months from start to primary completion across 9 trials still running at the 2026-10-09 snapshot; registered median of 18 months across 74 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Epiretinal Membrane trials in? (7)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 2
Phase 2 1
Phase 2/3 1
Phase 3 5
Phase 4 6
Not applicable 62
Observational 46

How many Epiretinal Membrane trials are recruiting? (8)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 3
Recruiting 7
Enrolling by invitation 2
Active, not recruiting 2
Completed 72

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Epiretinal Membrane trials? (1)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Alcon Research 4

Interventions as named in the registry (15)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Dexamethasone/Dexamethasone acetate 5
topical (eye drop) anti-inflammatories 1
Next Generation Ophthalmic Irrigating Solution (NGOIS) 1
Dexamethasone Intracanalicular Insert, 0.4 mg 1
Dicloftil 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Epiretinal Membrane trials report? (7)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Area of tractional retinal detachment versus retinoschisis surgery eye 1 1
Myocardial infarction 1 1
Ozurdex placment on fovea 1 1
Peptic ulcers-hospitalized for stomach pain 1 1
Persistent Corneal Epithelial Defect 1 1

Which publications cover Epiretinal Membrane? (154)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.

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