Condition (MeSH)
Thrombophilia
ClinicalTrials.gov lists 205 trials for Thrombophilia or a narrower condition beneath it. Takeda has the most among industry and government lead sponsors, with 7.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials per phase (log scale)
1 more section with rows
84 of the 205 trials are tagged with Thrombophilia itself; the rest are tagged with a narrower condition beneath it.
When did Thrombophilia trials start? (29)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 24
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 9 |
| 2025 | 9 |
| 2024 | 13 |
| 2023 | 5 |
| 2022 | 13 |
| 2021 | 12 |
| 2020 | 24 |
| 2019 | 6 |
| 2018 | 12 |
| 2017 | 7 |
Showing 10 of 29 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 12 trials starting in 2026 and about 11 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
Prediction, not a registry value: median of 36 months from start to primary completion across 7 trials still running at the 2026-10-09 snapshot; registered median of 22 months across 117 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Thrombophilia trials in? (9)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 6 |
| Phase 1/2 | 1 |
| Phase 2 | 25 |
| Phase 2/3 | 4 |
| Phase 3 | 25 |
| Phase 4 | 9 |
| Not applicable | 22 |
| Observational | 112 |
| Expanded access | 1 |
How many Thrombophilia trials are recruiting? (8)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 11 |
| Recruiting | 22 |
| Active, not recruiting | 6 |
| Completed | 94 |
| Approved for marketing | 1 |
Showing 5 of 8 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Thrombophilia trials? (8)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Takeda | 7 |
| Baxalta now part of Shire | 5 |
| Bayer | 4 |
| Kyowa Kirin Co., Ltd. | 4 |
| Octapharma | 4 |
Showing 5 of 8 sponsors.
Which drugs are being tested for Thrombophilia? (6)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Caplacizumab | 8 |
| RITUXIMAB | 7 |
| TAK-755 | 5 |
| LOVENOX | 5 |
| KW-3357 | 5 |
Showing 5 of 6 drugs.
Interventions as named in the registry (9)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| EC Aspirin | 8 |
| Fragmin P Forte (dalteparin sodium) | 3 |
| Plasma Exchange | 3 |
| Low Heparin Molecular Weight | 2 |
| thrombophilia screening | 2 |
Showing 5 of 9 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Thrombophilia trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Thrombotic thrombocytopenic purpura | 75 | 5 |
| Death | 44 | 1 |
| Thrombotic Thrombocytopenic Purpura | 19 | 1 |
| Epistaxis | 8 | 3 |
| Haemorrhage | 7 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Thrombophilia? (229)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Assessment of thrombophilia in patients with lupus anticoagulant. | Thrombosis research | 2025 | Yes |
| Edoxaban for the treatment of hypercoagulability and cerebral thromboembolism associated with cancer: A randomized clinical trial of biomarker targets. | International journal of stroke : official journal of the International Stroke Society | 2024 | Yes |
| Venous thromboembolism characteristics and outcomes among RIETE patients tested and untested for inherited thrombophilia. | Blood advances | 2024 | Yes |
| Prognostic impact of hypercoagulability and impaired fibrinolysis in acute myocardial infarction. | European heart journal | 2023 | Yes |
| Evaluation of Patients with Neonatal Thrombosis. | Indian journal of pediatrics | 2023 | Yes |
Showing 5 of 229 publications.
Sub-conditions in MeSH (6)
MeSH descendants one level down with at least one trial, most trials first.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence and rare-disease identity.