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Condition (MeSH)

Shoulder Pain

ClinicalTrials.gov lists 676 trials for Shoulder Pain or a narrower condition beneath it. Zimmer Biomet has the most among industry and government lead sponsors, with 9.

MeSH D020069 Musculoskeletal Diseases C05 C23
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Phase 1 Phase 1 10 Phase 1/2 Phase 1/2 3 Phase 2 Phase 2 16 Phase 2/3 Phase 2/3 3 Phase 3 Phase 3 16 Phase 4 Phase 4 37 Not applicable Not applicable 464 Observational Observational 127 Phase 1 Phase 1 10 Phase 1/2 Phase 1/2 3 Phase 2 Phase 2 16 Phase 2/3 Phase 2/3 3 Phase 3 Phase 3 16 Phase 4 Phase 4 37 Not applicable Not applicable 464 Observational Observational 127

Trials per phase (log scale)

676 of the 676 trials are tagged with Shoulder Pain itself; the rest are tagged with a narrower condition beneath it.

Get the Shoulder Pain report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Shoulder Pain trials start? (26)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 2 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 67

1999: 1 trials (Observational 1) 2001: 1 trials (Not applicable 1) 2003: 2 trials (Not applicable 1, Phase 1/2 1) 2004: 4 trials (Not applicable 1, Phase 3 2, Phase 1 1) 2005: 3 trials (Not applicable 2, Phase 3 1) 2006: 4 trials (Phase 3 3, Phase 2 1) 2007: 6 trials (Not applicable 2, Phase 4 1, Phase 3 1, Phase 2 2) 2008: 13 trials (Observational 1, Not applicable 7, Phase 4 1, Phase 3 2, Phase 2 2) 2009: 8 trials (Observational 3, Not applicable 3, Phase 4 1, Phase 3 1) 2010: 13 trials (Observational 3, Not applicable 8, Phase 4 2) 2011: 11 trials (Observational 1, Not applicable 4, Phase 4 1, Phase 3 2, Phase 2 2, Phase 1 1) 2012: 19 trials (Observational 4, Not applicable 8, Phase 4 2, Phase 3 1, Phase 2/3 1, Phase 2 3) 2013: 13 trials (Observational 2, Not applicable 4, Phase 4 3, Phase 2 3, Phase 1/2 1) 2014: 27 trials (Observational 3, Not applicable 19, Phase 4 3, Phase 1 2) 2015: 22 trials (Observational 5, Not applicable 15, Phase 4 2) 2016: 25 trials (Observational 6, Not applicable 16, Phase 4 2, Phase 2 1) 2017: 22 trials (Observational 6, Not applicable 14, Phase 1 2) 2018: 35 trials (Observational 8, Not applicable 25, Phase 4 1, Phase 3 1) 2019: 46 trials (Observational 12, Not applicable 24, Phase 4 6, Phase 2/3 1, Phase 2 1, Phase 1/2 1, Phase 1 1) 2020: 42 trials (Observational 10, Not applicable 29, Phase 4 2, Phase 2 1) 2021: 48 trials (Observational 5, Not applicable 38, Phase 4 3, Phase 3 1, Phase 1 1) 2022: 66 trials (Observational 10, Not applicable 54, Phase 4 1, Phase 1 1) 2023: 59 trials (Observational 13, Not applicable 41, Phase 4 3, Phase 3 1, Phase 2/3 1) 2024: 51 trials (Observational 11, Not applicable 39, Phase 4 1) 2025: 67 trials (Observational 12, Not applicable 54, Phase 4 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 65
2025 67
2024 51
2023 59
2022 66
2021 48
2020 42
2019 46
2018 35
2017 22

Forecast of the full-year count, planned starts included, not rows of this table: about 80 trials starting in 2026 and about 67 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 23 months from start to primary completion across 66 trials still running at the 2026-10-09 snapshot; registered median of 11 months across 436 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Shoulder Pain trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 10
Phase 1/2 3
Phase 2 16
Phase 2/3 3
Phase 3 16
Phase 4 37
Not applicable 464
Observational 127

How many Shoulder Pain trials are recruiting? (9)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 48
Recruiting 59
Enrolling by invitation 12
Active, not recruiting 18
Completed 397

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Shoulder Pain trials? (1)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Zimmer Biomet 9

Which drugs are being tested for Shoulder Pain? (3)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
+/- Bupivacaine HCl 12
Corticosteroid 6
METHYLPREDNISOLONE 4

Interventions as named in the registry (12)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Interscalene Block 8
Exercise 8
[PRP] platelet rich plasma 7
Ropivacaine 2 % 5
Control (placebo) group 5

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Shoulder Pain trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Desistance 47 1
Cardiac Event 4 1
Seizure 4 3
Syncope 3 1
other Musculoskeletal Injury 3 1

Which publications cover Shoulder Pain? (1,099)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.

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