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Condition (MeSH)

Dyskinesias

ClinicalTrials.gov lists 1,628 trials for Dyskinesias or a narrower condition beneath it. National Institute of Neurological Disorders and Stroke (NINDS) has the most among industry and government lead sponsors, with 76.

MeSH D020820 Nervous System Diseases C10 C23
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Phase 1 Phase 1 108 Phase 1/2 Phase 1/2 49 Phase 2 Phase 2 231 Phase 2/3 Phase 2/3 33 Phase 3 Phase 3 150 Phase 4 Phase 4 115 Not applicable Not applicable 518 Observational Observational 419 Phase 1 Phase 1 108 Phase 1/2 Phase 1/2 49 Phase 2 Phase 2 231 Phase 2/3 Phase 2/3 33 Phase 3 Phase 3 150 Phase 4 Phase 4 115 Not applicable Not applicable 518 Observational Observational 419

Trials per phase

1 more section with rows

173 of the 1,628 trials are tagged with Dyskinesias itself; the rest are tagged with a narrower condition beneath it.

Get the Dyskinesias report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Dyskinesias trials start? (35)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 4 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 103

1990: 1 trials (Observational 1) 1992: 1 trials (Observational 1) 1993: 1 trials (Observational 1) 1995: 1 trials (Phase 3 1) 1996: 1 trials (Observational 1) 1997: 3 trials (Observational 1, Phase 2/3 1, Phase 1 1) 1998: 3 trials (Observational 1, Phase 3 1, Phase 2 1) 1999: 8 trials (Observational 1, Not applicable 1, Phase 4 1, Phase 3 1, Phase 2 3, Phase 1 1) 2000: 11 trials (Observational 5, Phase 4 2, Phase 2 3, Phase 1 1) 2001: 19 trials (Observational 6, Not applicable 3, Phase 4 1, Phase 3 1, Phase 2 4, Phase 1/2 2, Phase 1 2) 2002: 22 trials (Observational 6, Not applicable 4, Phase 4 3, Phase 3 2, Phase 2 6, Phase 1/2 1) 2003: 26 trials (Observational 8, Not applicable 3, Phase 4 6, Phase 3 6, Phase 2 1, Phase 1 2) 2004: 25 trials (Observational 5, Not applicable 2, Phase 4 2, Phase 3 6, Phase 2/3 1, Phase 2 5, Phase 1/2 1, Phase 1 3) 2005: 40 trials (Observational 10, Not applicable 4, Phase 4 2, Phase 3 5, Phase 2/3 1, Phase 2 15, Phase 1/2 2, Phase 1 1) 2006: 37 trials (Observational 10, Not applicable 4, Phase 4 4, Phase 3 8, Phase 2/3 1, Phase 2 7, Phase 1/2 2, Phase 1 1) 2007: 36 trials (Observational 7, Not applicable 7, Phase 4 10, Phase 2 9, Phase 1 3) 2008: 41 trials (Observational 6, Not applicable 10, Phase 4 7, Phase 3 7, Phase 2/3 1, Phase 2 4, Phase 1/2 1, Phase 1 5) 2009: 57 trials (Observational 8, Not applicable 9, Phase 4 3, Phase 3 11, Phase 2/3 2, Phase 2 9, Phase 1/2 1, Phase 1 14) 2010: 39 trials (Observational 16, Not applicable 7, Phase 4 3, Phase 3 2, Phase 2/3 2, Phase 2 8, Phase 1 1) 2011: 69 trials (Observational 19, Not applicable 14, Phase 4 5, Phase 3 4, Phase 2/3 3, Phase 2 18, Phase 1 6) 2012: 62 trials (Observational 18, Not applicable 10, Phase 4 7, Phase 3 3, Phase 2 18, Phase 1/2 1, Phase 1 5) 2013: 78 trials (Observational 18, Not applicable 25, Phase 4 6, Phase 3 13, Phase 2/3 1, Phase 2 8, Phase 1/2 4, Phase 1 3) 2014: 60 trials (Observational 15, Not applicable 17, Phase 4 5, Phase 3 8, Phase 2/3 1, Phase 2 10, Phase 1/2 2, Phase 1 2) 2015: 76 trials (Observational 14, Not applicable 28, Phase 4 7, Phase 3 5, Phase 2/3 1, Phase 2 13, Phase 1/2 2, Phase 1 6) 2016: 61 trials (Observational 18, Not applicable 24, Phase 4 6, Phase 3 3, Phase 2/3 2, Phase 2 5, Phase 1/2 1, Phase 1 2) 2017: 77 trials (Observational 20, Not applicable 28, Phase 4 4, Phase 3 6, Phase 2/3 3, Phase 2 7, Phase 1/2 6, Phase 1 3) 2018: 72 trials (Observational 15, Not applicable 30, Phase 4 5, Phase 3 7, Phase 2 8, Phase 1/2 1, Phase 1 6) 2019: 92 trials (Observational 30, Not applicable 32, Phase 4 5, Phase 3 10, Phase 2/3 1, Phase 2 6, Phase 1/2 3, Phase 1 5) 2020: 71 trials (Observational 21, Not applicable 29, Phase 4 1, Phase 3 7, Phase 2/3 1, Phase 2 6, Phase 1/2 3, Phase 1 3) 2021: 98 trials (Observational 31, Not applicable 37, Phase 4 2, Phase 3 4, Phase 2/3 4, Phase 2 14, Phase 1/2 2, Phase 1 4) 2022: 80 trials (Observational 22, Not applicable 27, Phase 4 1, Phase 3 8, Phase 2/3 1, Phase 2 12, Phase 1/2 1, Phase 1 8) 2023: 75 trials (Observational 21, Not applicable 39, Phase 4 6, Phase 2 5, Phase 1/2 1, Phase 1 3) 2024: 103 trials (Observational 32, Not applicable 44, Phase 4 2, Phase 3 7, Phase 2/3 2, Phase 2 8, Phase 1/2 1, Phase 1 7) 2025: 94 trials (Observational 19, Not applicable 47, Phase 4 5, Phase 3 4, Phase 2/3 2, Phase 2 9, Phase 1/2 5, Phase 1 3)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 70
2025 94
2024 103
2023 75
2022 80
2021 98
2020 71
2019 92
2018 72
2017 77

Forecast of the full-year count, planned starts included, not rows of this table: about 91 trials starting in 2026 and about 92 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 148 trials still running at the 2026-10-09 snapshot; registered median of 23 months across 969 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Dyskinesias trials in? (9)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 108
Phase 1/2 49
Phase 2 231
Phase 2/3 33
Phase 3 150
Phase 4 115
Not applicable 518
Observational 419
Expanded access 5

How many Dyskinesias trials are recruiting? (12)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 47
Recruiting 205
Enrolling by invitation 14
Active, not recruiting 57
Available 1

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Dyskinesias trials? (9)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Institute of Neurological Disorders and Stroke (NINDS) 76
Neurocrine Biosciences 18
Institut National de la Santé Et de la Recherche Médicale, France 17
BioXcel Therapeutics Inc 12
Ipsen 12

Which drugs are being tested for Dyskinesias? (6)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
DEXMEDETOMIDINE 26
Valbenazine 11
Levodopa 10
Pridopidine 10
AFQ056 8

Interventions as named in the registry (9)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
type A botulinum toxin 39
IR Risperidone 13
Transcranial Magnetic Stimulation 12
Haloperidol-Haloperidol 12
IM olanzapine 11

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Dyskinesias trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Fall 122 40
Pneumonia 96 47
Syncope 53 31
COMPLICATION OF DEVICE INSERTION 45 5
PNEUMONIA 43 7

Which publications cover Dyskinesias? (157)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (13)

MeSH descendants one level down with at least one trial, most trials first.

+3 more sub-conditions

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages