Condition (MeSH)
Mannosidase Deficiency Diseases
ClinicalTrials.gov lists 28 trials for Mannosidase Deficiency Diseases or a narrower condition beneath it.
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Trials per phase
5 of the 28 trials are tagged with Mannosidase Deficiency Diseases itself; the rest are tagged with a narrower condition beneath it.
When did Mannosidase Deficiency Diseases trials start? (15)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 3
- Observational
Top of scale: 4
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2025 | 1 |
| 2021 | 1 |
| 2020 | 1 |
| 2018 | 2 |
| 2016 | 1 |
| 2015 | 1 |
| 2014 | 4 |
| 2013 | 2 |
| 2012 | 3 |
| 2011 | 2 |
Showing 10 of 15 earlier years.
No forecast is made for this condition: it averages 0.2 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: none of the 28 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Mannosidase Deficiency Diseases trials in? (6)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 2 |
| Phase 1/2 | 2 |
| Phase 2 | 8 |
| Phase 3 | 6 |
| Observational | 9 |
| Expanded access | 1 |
How many Mannosidase Deficiency Diseases trials are recruiting? (7)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Recruiting | 6 |
| Active, not recruiting | 1 |
| Available | 1 |
| Completed | 13 |
| Terminated | 3 |
Showing 5 of 7 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Mannosidase Deficiency Diseases trials? (6)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Chiesi Farmaceutici S.p.A. | 6 |
| Zymenex A/S | 6 |
| Aldagen | 1 |
| CENTOGENE GmbH Rostock | 1 |
| Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 1 |
Showing 5 of 6 sponsors.
Which drugs are being tested for Mannosidase Deficiency Diseases? (3)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Lamazym | 11 |
| Cytoxan | 2 |
| Busulfan | 2 |
Interventions as named in the registry (12)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Alemtuzumab s.c. | 3 |
| Stem Cell Transplantation | 2 |
| cALD HR-D (High-Risk, Regimen C) | 1 |
| Busulfan, Cyclophosphamide, ATG | 1 |
| Hematopoetic Stem Cell Transplantation | 1 |
Showing 5 of 12 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Mannosidase Deficiency Diseases trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Death | 6 | 1 |
| Auto recovery | 2 | 1 |
| Diarrhea | 2 | 1 |
| Graft failure | 2 | 1 |
| Pericardial Effusion | 2 | 1 |
Showing 5 of 10 adverse events.
Sub-conditions in MeSH (2)
MeSH descendants one level down with at least one trial, most trials first.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: publications, prevalence, and rare-disease identity.