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Condition (MeSH)

Labor Pain

ClinicalTrials.gov lists 416 trials for Labor Pain or a narrower condition beneath it.

MeSH D048949 Pathological Conditions, Signs and Symptoms C23
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Phase 1 Phase 1 4 Phase 2 Phase 2 10 Phase 2/3 Phase 2/3 5 Phase 3 Phase 3 15 Phase 4 Phase 4 42 Not applicable Not applicable 279 Observational Observational 61 Phase 1 Phase 1 4 Phase 2 Phase 2 10 Phase 2/3 Phase 2/3 5 Phase 3 Phase 3 15 Phase 4 Phase 4 42 Not applicable Not applicable 279 Observational Observational 61

Trials per phase (log scale)

416 of the 416 trials are tagged with Labor Pain itself; the rest are tagged with a narrower condition beneath it.

Get the Labor Pain report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Labor Pain trials start? (27)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 43

1998: 1 trials (Phase 3 1) 2000: 1 trials (Observational 1) 2001: 1 trials (Not applicable 1) 2003: 2 trials (Not applicable 1, Phase 4 1) 2004: 1 trials (Phase 4 1) 2005: 1 trials (Observational 1) 2006: 5 trials (Observational 2, Not applicable 2, Phase 4 1) 2007: 4 trials (Observational 1, Not applicable 3) 2008: 8 trials (Observational 1, Not applicable 5, Phase 4 1, Phase 1 1) 2009: 9 trials (Observational 2, Not applicable 3, Phase 4 1, Phase 3 2, Phase 2 1) 2010: 8 trials (Observational 1, Not applicable 2, Phase 4 2, Phase 3 2, Phase 2/3 1) 2011: 10 trials (Not applicable 6, Phase 4 1, Phase 3 2, Phase 2/3 1) 2012: 12 trials (Observational 2, Not applicable 3, Phase 4 3, Phase 2/3 1, Phase 2 2, Phase 1 1) 2013: 9 trials (Observational 2, Not applicable 3, Phase 4 2, Phase 2 2) 2014: 10 trials (Observational 2, Not applicable 6, Phase 4 2) 2015: 11 trials (Not applicable 8, Phase 4 2, Phase 3 1) 2016: 23 trials (Observational 4, Not applicable 14, Phase 4 3, Phase 3 2) 2017: 25 trials (Observational 6, Not applicable 10, Phase 4 6, Phase 3 1, Phase 2/3 1, Phase 2 1) 2018: 20 trials (Observational 1, Not applicable 18, Phase 4 1) 2019: 27 trials (Observational 1, Not applicable 23, Phase 4 1, Phase 2 1, Phase 1 1) 2020: 26 trials (Observational 5, Not applicable 17, Phase 4 2, Phase 3 1, Phase 1 1) 2021: 43 trials (Observational 6, Not applicable 31, Phase 4 4, Phase 3 1, Phase 2 1) 2022: 34 trials (Observational 7, Not applicable 24, Phase 4 1, Phase 3 1, Phase 2 1) 2023: 27 trials (Observational 6, Not applicable 18, Phase 4 1, Phase 2/3 1, Phase 2 1) 2024: 35 trials (Observational 4, Not applicable 29, Phase 4 2) 2025: 30 trials (Observational 2, Not applicable 27, Phase 4 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 32
2025 30
2024 35
2023 27
2022 34
2021 43
2020 26
2019 27
2018 20
2017 25

Forecast of the full-year count, planned starts included, not rows of this table: about 39 trials starting in 2026 and about 34 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 25 months from start to primary completion across 30 trials still running at the 2026-10-09 snapshot; registered median of 11 months across 288 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Labor Pain trials in? (7)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 4
Phase 2 10
Phase 2/3 5
Phase 3 15
Phase 4 42
Not applicable 279
Observational 61

How many Labor Pain trials are recruiting? (8)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 27
Recruiting 21
Enrolling by invitation 5
Active, not recruiting 12
Completed 262

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which drugs are being tested for Labor Pain? (5)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
FENTANYL 15
+/- Bupivacaine HCl 12
Sufentanil 7
DEXMEDETOMIDINE 4
Remifentanil 4

Interventions as named in the registry (10)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Ropivacaine 2 % 9
Epidural Analgesia 7
A3: Acetaminophen (Tylenol caplets®, from Janssen-Cilag, S.A. de C.V.) 7
combined spinal-epidural analgesia 6
Dural puncture epidural (DPE) 5

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Labor Pain trials report? (4)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Oxygen saturation lower than 92% 11 1
Cord pH < 7.1 3 1
Cesarean Section for Fetal Distress 0 1
Nausea 0 1

Which publications cover Labor Pain? (248)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: lead sponsors, prevalence, rare-disease identity, and sub-conditions in mesh.

Browse all condition evidence pages