Condition (MeSH)
Morning Sickness
ClinicalTrials.gov lists 46 trials for Morning Sickness or a narrower condition beneath it.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials per phase
9 of the 46 trials are tagged with Morning Sickness itself; the rest are tagged with a narrower condition beneath it.
When did Morning Sickness trials start? (19)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1/2
- Phase 2
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 6
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 3 |
| 2025 | 5 |
| 2024 | 3 |
| 2023 | 2 |
| 2022 | 6 |
| 2021 | 1 |
| 2020 | 1 |
| 2019 | 3 |
| 2018 | 1 |
| 2017 | 3 |
Showing 10 of 19 earlier years.
No forecast is made for this condition: it averages 3.8 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 4 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Morning Sickness trials in? (6)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1/2 | 2 |
| Phase 2 | 3 |
| Phase 3 | 5 |
| Phase 4 | 3 |
| Not applicable | 17 |
| Observational | 16 |
How many Morning Sickness trials are recruiting? (8)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 2 |
| Recruiting | 3 |
| Active, not recruiting | 1 |
| Completed | 28 |
| Suspended | 1 |
Showing 5 of 8 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Morning Sickness trials? (5)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Duchesnay Inc. | 3 |
| Kayseri Education and Research Hospital | 3 |
| Adana Numune Training and Research Hospital | 1 |
| Ankara Etlik City Hospital | 1 |
| Dr. Lutfi Kirdar Kartal Training and Research Hospital | 1 |
Interventions as named in the registry (15)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Ondansetron - Parts A + B | 3 |
| Mirtazapine Pill | 2 |
| Doxylamine succinate 10 mg + Pyridoxine HCl 10 mg | 2 |
| Metclopramide | 2 |
| No Interventions | 1 |
Showing 5 of 15 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Morning Sickness trials report? (6)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Abortion missed | 2 | 1 |
| Abortion spontaneous | 2 | 1 |
| Bile duct stone | 1 | 1 |
| Foetal disorder | 1 | 1 |
| Intra-uterine Death | 1 | 1 |
Showing 5 of 6 adverse events.
Which publications cover Morning Sickness? (23)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Prepregnancy metformin use associated with lower risk of severe nausea and vomiting of pregnancy and hyperemesis gravidarum. | American journal of obstetrics and gynecology | 2025 | Yes |
| Measuring the severity of nausea and vomiting of pregnancy; a 20-year perspective on the use of the pregnancy-unique quantification of emesis (PUQE). | Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology | 2021 | Yes |
| Nausea, vomiting and poor appetite during pregnancy and adverse birth outcomes in rural Nepal: an observational cohort study. | BMC pregnancy and childbirth | 2020 | Yes |
| The health and quality of life of Thalidomide survivors as they age - Evidence from a UK survey. | PloS one | 2019 | Yes |
| ACOG Practice Bulletin No. 189: Nausea And Vomiting Of Pregnancy. | Obstetrics and gynecology | 2018 | Yes |
Showing 5 of 23 publications.
Sub-conditions in MeSH (1)
MeSH descendants one level down with at least one trial, most trials first.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence and rare-disease identity.