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Condition (MeSH)

Post-Traumatic Headache

ClinicalTrials.gov lists 185 trials for Post-Traumatic Headache or a narrower condition beneath it.

MeSH D051298 Nervous System Diseases C10
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Phase 1 Phase 1 6 Phase 1/2 Phase 1/2 5 Phase 2 Phase 2 10 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 5 Phase 4 Phase 4 8 Not applicable Not applicable 129 Observational Observational 21 Phase 1 Phase 1 6 Phase 1/2 Phase 1/2 5 Phase 2 Phase 2 10 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 5 Phase 4 Phase 4 8 Not applicable Not applicable 129 Observational Observational 21

Trials per phase (log scale)

185 of the 185 trials are tagged with Post-Traumatic Headache itself; the rest are tagged with a narrower condition beneath it.

Get the Post-Traumatic Headache report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Post-Traumatic Headache trials start? (19)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 31

2005: 2 trials (Phase 4 1, Phase 2 1) 2006: 2 trials (Not applicable 1, Phase 4 1) 2007: 1 trials (Observational 1) 2009: 1 trials (Observational 1) 2010: 2 trials (Not applicable 1, Phase 4 1) 2012: 5 trials (Not applicable 3, Phase 2/3 1, Phase 1/2 1) 2013: 6 trials (Not applicable 2, Phase 4 1, Phase 2 2, Phase 1 1) 2015: 3 trials (Not applicable 3) 2016: 5 trials (Observational 1, Not applicable 2, Phase 4 1, Phase 1/2 1) 2017: 5 trials (Not applicable 1, Phase 3 1, Phase 2 1, Phase 1/2 2) 2018: 7 trials (Not applicable 6, Phase 3 1) 2019: 12 trials (Observational 2, Not applicable 6, Phase 2 1, Phase 1 3) 2020: 13 trials (Observational 1, Not applicable 9, Phase 4 2, Phase 2 1) 2021: 8 trials (Observational 2, Not applicable 4, Phase 4 1, Phase 2 1) 2022: 31 trials (Observational 3, Not applicable 26, Phase 2 1, Phase 1/2 1) 2023: 14 trials (Observational 1, Not applicable 12, Phase 3 1) 2024: 17 trials (Observational 1, Not applicable 14, Phase 1 2) 2025: 31 trials (Observational 5, Not applicable 24, Phase 3 1, Phase 2 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 19
2025 31
2024 17
2023 14
2022 31
2021 8
2020 13
2019 12
2018 7
2017 5

Forecast of the full-year count, planned starts included, not rows of this table: about 25 trials starting in 2026 and about 26 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 35 months from start to primary completion across 22 trials still running at the 2026-10-09 snapshot; registered median of 16 months across 108 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Post-Traumatic Headache trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 6
Phase 1/2 5
Phase 2 10
Phase 2/3 1
Phase 3 5
Phase 4 8
Not applicable 129
Observational 21

How many Post-Traumatic Headache trials are recruiting? (8)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 16
Recruiting 25
Enrolling by invitation 2
Active, not recruiting 6
Completed 94

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Interventions as named in the registry (15)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Conventional Therapy 5
Metclopramide 3
Physiotherapy 2
Conventional Treatment 2
T.Prazosin 2

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Post-Traumatic Headache trials report? (8)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Planned surgical procedure 2 1
planned surgical procedure 2 1
Cholelithiasis 1 1
Gastrointestinal haemorrhage 1 1
Hypotension 1 1

Which publications cover Post-Traumatic Headache? (128)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: lead sponsors, prevalence, rare-disease identity, and sub-conditions in mesh.

Browse all condition evidence pages