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Condition (MeSH)

Hypercalciuria

ClinicalTrials.gov lists 31 trials for Hypercalciuria or a narrower condition beneath it.

MeSH D053565 Pathological Conditions, Signs and Symptoms C23
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Phase 1 Phase 1 2 Phase 2 Phase 2 6 Phase 2/3 Phase 2/3 2 Phase 3 Phase 3 4 Phase 4 Phase 4 3 Not applicable Not applicable 8 Observational Observational 6 Phase 1 Phase 1 2 Phase 2 Phase 2 6 Phase 2/3 Phase 2/3 2 Phase 3 Phase 3 4 Phase 4 Phase 4 3 Not applicable Not applicable 8 Observational Observational 6

Trials per phase

31 of the 31 trials are tagged with Hypercalciuria itself; the rest are tagged with a narrower condition beneath it.

Get the Hypercalciuria report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Hypercalciuria trials start? (20)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 4

1995: 1 trials (Phase 3 1) 1998: 1 trials (Not applicable 1) 2005: 3 trials (Not applicable 1, Phase 4 1, Phase 2/3 1) 2006: 1 trials (Not applicable 1) 2007: 1 trials (Not applicable 1) 2008: 1 trials (Observational 1) 2009: 2 trials (Not applicable 1, Phase 3 1) 2011: 1 trials (Phase 4 1) 2012: 1 trials (Phase 2 1) 2013: 1 trials (Phase 2 1) 2014: 1 trials (Not applicable 1) 2015: 2 trials (Observational 1, Phase 2/3 1) 2017: 1 trials (Phase 2 1) 2018: 4 trials (Not applicable 1, Phase 3 1, Phase 2 1, Phase 1 1) 2019: 3 trials (Not applicable 1, Phase 2 1, Phase 1 1) 2021: 2 trials (Observational 1, Phase 2 1) 2022: 1 trials (Observational 1) 2023: 1 trials (Phase 3 1) 2024: 1 trials (Observational 1) 2025: 1 trials (Phase 4 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2025 1
2024 1
2023 1
2022 1
2021 2
2019 3
2018 4
2017 1
2015 2
2014 1

No forecast is made for this condition: it averages 0.8 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Hypercalciuria trials in? (7)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 2
Phase 2 6
Phase 2/3 2
Phase 3 4
Phase 4 3
Not applicable 8
Observational 6

How many Hypercalciuria trials are recruiting? (6)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Recruiting 3
Active, not recruiting 4
Completed 15
Terminated 3
Withdrawn 1

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Hypercalciuria trials? (2)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Calcilytix Therapeutics, Inc., a BridgeBio company 2
VA New York Harbor Healthcare System 2

Which drugs are being tested for Hypercalciuria? (3)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Calcium-vitamin D3 2
Chlorthalidone 2
Calcium/Vitamin D 2

Interventions as named in the registry (12)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
HCTZ-hydrochlorothiazide 2
Rifampicin 2
open-label PTH(1-84) 1
Thiazide 1
Potassium sparing diuretic 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Hypercalciuria trials report? (7)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Hypocalcemia 13 1
Surgery elective 3 1
Swelling of face, tongue 3 1
Infection in uterus 2 1
Pneumonia 2 1

Which publications cover Hypercalciuria? (45)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Treatment of Autosomal Dominant Hypocalcemia Type 1 With the Calcilytic NPSP795 (SHP635). Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2019 Yes
Primary hyperparathyroidism, hypercalciuria, and bone recovery after parathyroidectomy. Surgery 2017 Yes
Kidney Calculi: Pathophysiology and as a Systemic Disorder. Iranian journal of kidney diseases 2017 Yes
Hypomagnesemia and mortality in patients admitted to intensive care unit: a systematic review and meta-analysis. QJM : monthly journal of the Association of Physicians 2016 Yes
Hypercalcemia, hypercalciuria, and kidney stones in long-term studies of vitamin D supplementation: a systematic review and meta-analysis. The American journal of clinical nutrition 2016 Yes

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.

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