Condition (MeSH)
Laryngomalacia
ClinicalTrials.gov lists 11 trials for Laryngomalacia or a narrower condition beneath it. Tel-Aviv Sourasky Medical Center has the most among industry and government lead sponsors, with 1.
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Trials per phase
11 of the 11 trials are tagged with Laryngomalacia itself; the rest are tagged with a narrower condition beneath it.
When did Laryngomalacia trials start? (9)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Not applicable
- Observational
Top of scale: 2
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 1 |
| 2024 | 2 |
| 2022 | 1 |
| 2020 | 1 |
| 2016 | 1 |
| 2013 | 2 |
| 2007 | 1 |
| 2006 | 1 |
| 2002 | 1 |
No forecast is made for this condition: it averages 0.8 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: none of the 11 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Laryngomalacia trials in? (4)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 1 |
| Phase 1/2 | 1 |
| Not applicable | 5 |
| Observational | 4 |
How many Laryngomalacia trials are recruiting? (6)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 1 |
| Recruiting | 2 |
| Completed | 3 |
| Terminated | 2 |
| Withdrawn | 2 |
Showing 5 of 6 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Laryngomalacia trials? (1)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Tel-Aviv Sourasky Medical Center | 1 |
Which drugs are being tested for Laryngomalacia? (2)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Omeprazole 20 mg | 1 |
| Calcium/Vitamin D | 1 |
Interventions as named in the registry (3)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Famotidine FCT | 1 |
| PPI | 1 |
| ranitidine or famotidine | 1 |
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Laryngomalacia trials report? (5)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Hospital admission for viral infection | 3 | 1 |
| Hospital admission for seizure | 2 | 1 |
| Hospital admission for monitoring post-motor vehicle accident | 1 | 1 |
| Inguinal hernia with incarceration requiring surgery | 1 | 1 |
| Pediatric intensive care unit admission for respiratory distress following supraglottoplasty | 1 | 1 |
Which publications cover Laryngomalacia? (9)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Acid Suppression in Mild-Moderate Laryngomalacia Without GERD: A Randomized Controlled Trial. | The Laryngoscope | 2026 | Yes |
| Pepsin as a biomarker for laryngopharyngeal reflux in children with laryngomalacia. | The Laryngoscope | 2017 | Yes |
| Congenital laryngomalacia is related to exercise-induced laryngeal obstruction in adolescence. | Archives of disease in childhood | 2016 | Yes |
| Practice patterns in supraglottoplasty and perioperative care. | International journal of pediatric otorhinolaryngology | 2016 | Yes |
| A systematic review of laryngomalacia and acid reflux. | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery | 2012 | Yes |
Showing 5 of 9 publications.
Prevalence (6)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Congenital laryngomalacia | Annual incidence | 1-5 / 10 000 | Worldwide | Not stated | Exact |
| Congenital laryngomalacia | Annual incidence | 1-5 / 10 000 | Worldwide | Not stated | Exact |
| Congenital laryngomalacia | Point prevalence | Unknown | Worldwide | Not stated | Exact |
| Congenital laryngomalacia | Point prevalence | Unknown | Worldwide | Not stated | Unspecified |
| Congenital laryngomalacia | Annual incidence | 1-5 / 10 000 | Worldwide | Not stated | Unspecified |
Showing 5 of 6 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Congenital laryngomalacia | 2373 | Exact | Orphadata Science knowledge files, Product 1 |
| Congenital laryngomalacia | 2373 | Exact | Orphanet Rare Disease Ontology (ORDO) |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: sub-conditions in mesh.