Condition (MeSH)
Microscopic Polyangiitis
ClinicalTrials.gov lists 69 trials for Microscopic Polyangiitis or a narrower condition beneath it.
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Trials per phase
69 of the 69 trials are tagged with Microscopic Polyangiitis itself; the rest are tagged with a narrower condition beneath it.
When did Microscopic Polyangiitis trials start? (28)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 6
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 2 |
| 2025 | 2 |
| 2024 | 5 |
| 2023 | 2 |
| 2022 | 2 |
| 2021 | 1 |
| 2020 | 4 |
| 2019 | 3 |
| 2018 | 4 |
| 2017 | 1 |
Showing 10 of 28 earlier years.
No forecast is made for this condition: it averages 2.6 trial starts a year over the five years to September, under the 5 a year the method needs.
Prediction, not a registry value: median of 36 months from start to primary completion across 8 trials still running at the 2026-10-09 snapshot; registered median of 41 months across 42 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Microscopic Polyangiitis trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 2 |
| Phase 1/2 | 2 |
| Phase 2 | 11 |
| Phase 2/3 | 3 |
| Phase 3 | 12 |
| Phase 4 | 10 |
| Not applicable | 3 |
| Observational | 26 |
How many Microscopic Polyangiitis trials are recruiting? (7)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 1 |
| Recruiting | 10 |
| Active, not recruiting | 4 |
| Completed | 35 |
| Terminated | 8 |
Showing 5 of 7 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Microscopic Polyangiitis trials? (4)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| InflaRx GmbH | 2 |
| Novartis Pharmaceuticals | 2 |
| Alpine Immune Sciences, Inc. | 1 |
| Anthera Pharmaceuticals | 1 |
Which drugs are being tested for Microscopic Polyangiitis? (5)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| RITUXIMAB | 14 |
| Cytoxan | 7 |
| Prednisone | 4 |
| METHYLPREDNISOLONE | 4 |
| INFLIXIMAB | 2 |
Interventions as named in the registry (10)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Azathioprine Pill | 7 |
| Glucocorticoids | 4 |
| Mofetil Mycophenolate | 4 |
| Plasma Exchange | 3 |
| BLOOD SAMPLE | 2 |
Showing 5 of 10 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Microscopic Polyangiitis trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Infection | 250 | 1 |
| Other | 168 | 1 |
| Cardiovascular | 124 | 1 |
| Renal | 77 | 1 |
| Gastrointestinal | 73 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Microscopic Polyangiitis? (26)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| EULAR recommendations for the management of ANCA-associated vasculitis: 2022 update. | Annals of the rheumatic diseases | 2024 | Yes |
| Phase IIa Global Study Evaluating Rituximab for the Treatment of Pediatric Patients With Granulomatosis With Polyangiitis or Microscopic Polyangiitis. | Arthritis & rheumatology (Hoboken, N.J.) | 2022 | Yes |
| 2022 American College of Rheumatology/European Alliance of Associations for Rheumatology classification criteria for microscopic polyangiitis. | Annals of the rheumatic diseases | 2022 | Yes |
| Long-Term Safety of Rituximab in Granulomatosis With Polyangiitis and in Microscopic Polyangiitis. | Arthritis care & research | 2021 | Yes |
| Rituximab Biosimilar Prevents Poor Outcomes of Microscopic Polyangiitis and Granulomatosis with Polyangiitis as Effectively as Rituximab Originator. | Yonsei medical journal | 2020 | Yes |
Showing 5 of 26 publications.
Prevalence (63)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Microscopic polyangiitis | Point prevalence | 1-9 / 100 000 | United Kingdom | GB | Unspecified |
| Microscopic polyangiitis | Point prevalence | 1-9 / 100 000 | United Kingdom | GB | Exact |
| Microscopic polyangiitis | Point prevalence | 1-9 / 100 000 | United Kingdom | GB | Exact |
| Microscopic polyangiitis | Annual incidence | 1-9 / 1 000 000 | United Kingdom | GB | Unspecified |
| Microscopic polyangiitis | Annual incidence | 1-9 / 1 000 000 | United Kingdom | GB | Exact |
Showing 5 of 63 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Microscopic polyangiitis | 727 | Exact | Orphadata Science knowledge files, Product 1 |
| Microscopic polyangiitis | 727 | Exact | Orphanet Rare Disease Ontology (ORDO) |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: sub-conditions in mesh.