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Condition (MeSH)

Yellow Nail Syndrome

ClinicalTrials.gov lists 2 trials for Yellow Nail Syndrome or a narrower condition beneath it. Pfizer has the most among industry and government lead sponsors, with 2.

MeSH D056684 Congenital / Hereditary / Neonatal C16 C17 C23 Listed by Orphanet as a rare disease
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Trials started per year Trials started per year 2 Trials by phase Trials by phase 1 Trials by recruitment status Trials by recruitment status 1 Lead sponsors Lead sponsors 1 Serious adverse events in this condition's trials Serious adverse events in this condition's trials 10 Publications Publications 3 Prevalence Prevalence 6 Rare-disease identity Rare-disease identity 2 Trials started per year Trials started per year 2 Trials by phase Trials by phase 1 Trials by recruitment status Trials by recruitment status 1 Lead sponsors Lead sponsors 1 Serious adverse events in this condition's trials Serious adverse events in this condition's trials 10 Publications Publications 3 Prevalence Prevalence 6 Rare-disease identity Rare-disease identity 2

Rows recorded per section

1 section measured, none recorded · 1 not measured yet · 1 not computed

2 of the 2 trials are tagged with Yellow Nail Syndrome itself; the rest are tagged with a narrower condition beneath it.

Get the Yellow Nail Syndrome report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Yellow Nail Syndrome trials start? (2)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials started per year
Year Trials started
2011 1
2010 1

No forecast is made for this condition: it averages 0.0 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: none of the 2 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Yellow Nail Syndrome trials in? (1)

Shown in this order: phase order.

Trials by phase
Phase Trials
Phase 3 2

How many Yellow Nail Syndrome trials are recruiting? (1)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Completed 2

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Yellow Nail Syndrome trials? (1)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Pfizer 2

Which serious adverse events do Yellow Nail Syndrome trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Coronary artery disease (unrelated) 2 1
Osteoarthritis (unrelated) 2 1
Pulmonary embolism (unrelated) 2 2
Acute myocardial infarction (unrelated) 1 1
Anaemia (unrelated) 1 1

Which publications cover Yellow Nail Syndrome? (3)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Yellow nail syndrome: clinical experience in a series of 21 patients. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2014 Yes
Titanium, sinusitis, and the yellow nail syndrome. Biological trace element research 2011 Yes
Aetiology of bronchiectasis in Guangzhou, southern China. Respirology (Carlton, Vic.) 2015 No

Prevalence (6)

Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.

Prevalence
Orphanet disease Type Class Geography Jurisdiction Mapping relation
Lymphedema with yellow nails Point prevalence <1 / 1 000 000 Worldwide Not stated Unspecified
Lymphedema with yellow nails Cases families Worldwide Not stated Unspecified
Lymphedema with yellow nails Point prevalence <1 / 1 000 000 Worldwide Not stated Exact
Lymphedema with yellow nails Cases families Worldwide Not stated Exact
Lymphedema with yellow nails Cases families Worldwide Not stated Exact

Rare-disease identity (2)

Shown in this order: exact, broader, narrower, other.

Rare-disease identity
Orphanet disease ORPHA code Relation Source
Lymphedema with yellow nails 662 Exact Orphadata Science knowledge files, Product 1
Lymphedema with yellow nails 662 Exact Orphanet Rare Disease Ontology (ORDO)

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: sub-conditions in mesh.

Not computed for conditions with fewer than 10 trials: drugs tested.

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