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Condition (MeSH)

Candidiasis, Invasive

ClinicalTrials.gov lists 104 trials for Candidiasis, Invasive or a narrower condition beneath it. Pfizer has the most among industry and government lead sponsors, with 15.

MeSH D058365 Infections C01 Listed by Orphanet as a rare disease
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Phase 1 Phase 1 4 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 14 Phase 3 Phase 3 25 Phase 4 Phase 4 13 Not applicable Not applicable 9 Observational Observational 38 Phase 1 Phase 1 4 Phase 1/2 Phase 1/2 1 Phase 2 Phase 2 14 Phase 3 Phase 3 25 Phase 4 Phase 4 13 Not applicable Not applicable 9 Observational Observational 38

Trials per phase (log scale)

64 of the 104 trials are tagged with Candidiasis, Invasive itself; the rest are tagged with a narrower condition beneath it.

Get the Candidiasis, Invasive report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Candidiasis, Invasive trials start? (25)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 11

1999: 2 trials (Phase 3 1, Phase 2 1) 2001: 1 trials (Phase 2 1) 2003: 2 trials (Phase 3 2) 2004: 5 trials (Observational 2, Not applicable 1, Phase 3 2) 2006: 1 trials (Phase 3 1) 2007: 6 trials (Phase 4 3, Phase 3 1, Phase 1 2) 2008: 11 trials (Observational 2, Not applicable 1, Phase 4 3, Phase 3 2, Phase 2 1, Phase 1/2 1, Phase 1 1) 2009: 6 trials (Observational 2, Phase 3 3, Phase 2 1) 2010: 5 trials (Observational 2, Phase 3 1, Phase 2 2) 2011: 7 trials (Observational 6, Phase 3 1) 2012: 6 trials (Observational 4, Phase 4 1, Phase 3 1) 2013: 5 trials (Observational 2, Phase 4 1, Phase 3 1, Phase 1 1) 2014: 6 trials (Observational 3, Phase 4 1, Phase 2 2) 2015: 4 trials (Observational 2, Not applicable 1, Phase 2 1) 2016: 3 trials (Observational 2, Phase 2 1) 2017: 4 trials (Observational 1, Not applicable 1, Phase 3 2) 2018: 8 trials (Observational 3, Not applicable 2, Phase 4 1, Phase 3 1, Phase 2 1) 2019: 3 trials (Observational 1, Phase 4 1, Phase 2 1) 2020: 3 trials (Observational 1, Phase 3 1, Phase 2 1) 2021: 1 trials (Phase 3 1) 2022: 5 trials (Observational 1, Not applicable 1, Phase 4 1, Phase 3 1, Phase 2 1) 2023: 4 trials (Observational 1, Not applicable 2, Phase 3 1) 2024: 3 trials (Observational 2, Phase 3 1) 2025: 2 trials (Observational 1, Phase 3 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 1
2025 2
2024 3
2023 4
2022 5
2021 1
2020 3
2019 3
2018 8
2017 4

No forecast is made for this condition: it averages 3.0 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: 3 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Candidiasis, Invasive trials in? (7)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 4
Phase 1/2 1
Phase 2 14
Phase 3 25
Phase 4 13
Not applicable 9
Observational 38

How many Candidiasis, Invasive trials are recruiting? (6)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 3
Recruiting 5
Completed 73
Terminated 12
Withdrawn 4

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Candidiasis, Invasive trials? (8)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Pfizer 15
Astellas Pharma Inc 7
Merck Sharp & Dohme LLC 5
Scynexis, Inc. 4
Basilea Pharmaceutica 3

Which drugs are being tested for Candidiasis, Invasive? (4)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Anidulafungin 9
IBREXAFUNGERP 4
APX001 3
Amphotericin B Deoxycholate 2

Interventions as named in the registry (11)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Comparator: Micafungin sodium 17
MK0991, caspofungin acetate 14
Fluconazol 13
Voriconazole 1% 6
Active Anidulafungin 2

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Candidiasis, Invasive trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Septic shock 125 18
Sepsis 97 14
Respiratory failure 70 16
Pneumonia 51 16
Cardiac arrest 46 12

Which publications cover Candidiasis, Invasive? (57)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Prevalence (2)

Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.

Prevalence
Orphanet disease Type Class Geography Jurisdiction Mapping relation
Invasive candidiasis Annual incidence 1-9 / 100 000 France Not stated Unspecified
Invasive candidiasis Point prevalence Unknown Europe Not stated Unspecified

Sub-conditions in MeSH (1)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: rare-disease identity.

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