Condition (MeSH)
Stroke, Lacunar
ClinicalTrials.gov lists 21 trials for Stroke, Lacunar or a narrower condition beneath it. Synchron Medical, Inc. has the most among industry and government lead sponsors, with 2.
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Trials per phase
21 of the 21 trials are tagged with Stroke, Lacunar itself; the rest are tagged with a narrower condition beneath it.
When did Stroke, Lacunar trials start? (10)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 6
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2025 | 6 |
| 2024 | 1 |
| 2022 | 3 |
| 2021 | 2 |
| 2020 | 1 |
| 2019 | 2 |
| 2018 | 2 |
| 2016 | 2 |
| 2015 | 1 |
| 2003 | 1 |
No forecast is made for this condition: it averages 2.0 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 2 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Stroke, Lacunar trials in? (6)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 2 | 1 |
| Phase 2/3 | 1 |
| Phase 3 | 4 |
| Phase 4 | 1 |
| Not applicable | 9 |
| Observational | 5 |
How many Stroke, Lacunar trials are recruiting? (7)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 2 |
| Recruiting | 6 |
| Active, not recruiting | 1 |
| Completed | 6 |
| Terminated | 2 |
Showing 5 of 7 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Stroke, Lacunar trials? (1)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Synchron Medical, Inc. | 2 |
Which drugs are being tested for Stroke, Lacunar? (5)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| PHENYLEPHRINE | 2 |
| Butylphthalide | 1 |
| Carbogen | 1 |
| Isosorbide Mononitrate | 1 |
| Cilostazol | 1 |
Interventions as named in the registry (9)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| EC Aspirin | 1 |
| carbogen with or without phenyleprhine | 1 |
| prophylactic stroke medication | 1 |
| Clopidogrel 75 | 1 |
| ISMN XL and Cilostazol | 1 |
Showing 5 of 9 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Stroke, Lacunar trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Gastrointestinal | 21 | 1 |
| Cardiovascular | 18 | 1 |
| Other | 18 | 1 |
| Infection/sepsis | 9 | 1 |
| Genitourinary | 7 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Stroke, Lacunar? (55)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| High-intensity training in patients with lacunar stroke: A one-year follow-up. | Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association | 2023 | Yes |
| Dual Antiplatelet Therapy With Cilostazol for Secondary Prevention in Lacunar Stroke: Subanalysis of the CSPS.com Trial. | Stroke | 2023 | Yes |
| Isosorbide Mononitrate and Cilostazol Treatment in Patients With Symptomatic Cerebral Small Vessel Disease: The Lacunar Intervention Trial-2 (LACI-2) Randomized Clinical Trial. | JAMA neurology | 2023 | Yes |
| Systolic blood pressure and recurrent stroke in patients with different lesion patterns on diffusion weighted imaging. | Journal of clinical hypertension (Greenwich, Conn.) | 2022 | Yes |
| Intensive versus guideline-recommended blood pressure reduction in acute lacunar stroke with intravenous thrombolysis therapy: The ENCHANTED trial. | European journal of neurology | 2021 | Yes |
Showing 5 of 55 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.