Condition (MeSH)
Prodromal Symptoms
ClinicalTrials.gov lists 19 trials for Prodromal Symptoms or a narrower condition beneath it.
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Trials per phase
19 of the 19 trials are tagged with Prodromal Symptoms itself; the rest are tagged with a narrower condition beneath it.
When did Prodromal Symptoms trials start? (12)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 2
- Phase 4
- Not applicable
- Observational
Top of scale: 3
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 1 |
| 2025 | 2 |
| 2024 | 3 |
| 2023 | 1 |
| 2022 | 1 |
| 2021 | 3 |
| 2020 | 1 |
| 2019 | 2 |
| 2015 | 2 |
| 2013 | 1 |
Showing 10 of 12 earlier years.
No forecast is made for this condition: it averages 1.8 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 4 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Prodromal Symptoms trials in? (4)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 2 | 1 |
| Phase 4 | 1 |
| Not applicable | 14 |
| Observational | 3 |
How many Prodromal Symptoms trials are recruiting? (6)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Recruiting | 7 |
| Active, not recruiting | 1 |
| Completed | 6 |
| Terminated | 1 |
| Withdrawn | 1 |
Showing 5 of 6 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Prodromal Symptoms trials? (3)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Finnish Institute for Health and Welfare | 1 |
| Guangzhou Psychiatric Hospital | 1 |
| Vaccinex Inc. | 1 |
Which drugs are being tested for Prodromal Symptoms? (1)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| VX15/2503 | 1 |
Interventions as named in the registry (2)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Amisulpride Pill | 1 |
| Aerobic exercise | 1 |
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which publications cover Prodromal Symptoms? (156)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Advancements and Future Directions in Prevention Based on Evaluation for Individuals With Clinical High Risk of Psychosis: Insights From the SHARP Study. | Schizophrenia bulletin | 2025 | Yes |
| Effectiveness of Omega-3 Fatty Acids Versus Placebo in Subjects at Ultra-High Risk for Psychosis: The PURPOSE Randomized Clinical Trial. | Schizophrenia bulletin | 2025 | Yes |
| Overlap between perceived triggers, premonitory symptoms and symptom persistence across migraine phases: A REFORM study. | Cephalalgia : an international journal of headache | 2025 | Yes |
| Nutrition guidance within a multimodal intervention improves diet quality in prodromal Alzheimer's disease: Multimodal Preventive Trial for Alzheimer's Disease (MIND-AD<sub>mini</sub>). | Alzheimer's research & therapy | 2024 | Yes |
| Davunetide sex-dependently boosts memory in prodromal Alzheimer's disease. | Translational psychiatry | 2024 | Yes |
Showing 5 of 156 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.