Condition (MeSH)
Congenital Microtia
ClinicalTrials.gov lists 33 trials for Congenital Microtia or a narrower condition beneath it. Auregen Biotherapeutics, SA has the most among industry and government lead sponsors, with 3.
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Trials per phase
33 of the 33 trials are tagged with Congenital Microtia itself; the rest are tagged with a narrower condition beneath it.
When did Congenital Microtia trials start? (12)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 4
- Not applicable
- Observational
Top of scale: 5
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 4 |
| 2025 | 3 |
| 2024 | 4 |
| 2023 | 5 |
| 2022 | 5 |
| 2021 | 3 |
| 2020 | 4 |
| 2019 | 1 |
| 2018 | 1 |
| 2015 | 1 |
Showing 10 of 12 earlier years.
No forecast is made for this condition: it averages 4.6 trial starts a year over the five years to September, under the 5 a year the method needs.
Prediction, not a registry value: median of 27 months from start to primary completion across 6 trials still running at the 2026-10-09 snapshot; registered median of 21 months across 14 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Congenital Microtia trials in? (6)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 3 |
| Phase 1/2 | 3 |
| Phase 2 | 2 |
| Phase 4 | 2 |
| Not applicable | 15 |
| Observational | 8 |
How many Congenital Microtia trials are recruiting? (7)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 3 |
| Recruiting | 4 |
| Active, not recruiting | 2 |
| Completed | 9 |
| Terminated | 5 |
Showing 5 of 7 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Congenital Microtia trials? (2)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Auregen Biotherapeutics, SA | 3 |
| 3DBio Therapeutics | 1 |
Interventions as named in the registry (10)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Bactrim DS 800Mg-160Mg Tablet | 1 |
| Akkermansia muciniphila | 1 |
| [PRP] platelet rich plasma | 1 |
| Probiotic | 1 |
| Silicone Gel | 1 |
Showing 5 of 10 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which publications cover Congenital Microtia? (20)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Anxiety, Depression, Stress, and Self-Esteem in Turkish Parents of Children with Microtia. | The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association | 2024 | Yes |
| Our Evolution of Approaches to Microtia Reconstruction. | Facial plastic surgery clinics of North America | 2024 | Yes |
| A Two-Stage Method for Adult Congenital Microtia: The Essentials of 15-Year Experience. | The Laryngoscope | 2023 | Yes |
| Secondary ear reconstruction based on the Nagata method after unsatisfactory microtia surgery outcomes. | Journal of plastic, reconstructive & aesthetic surgery : JPRAS | 2023 | Yes |
| Secondary surgery for the unsatisfactory auricle after auricular reconstruction. | International journal of pediatric otorhinolaryngology | 2022 | Yes |
Showing 5 of 20 publications.
Prevalence (51)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Microtia | Prevalence at birth | 1-5 / 10 000 | United States | US | Exact |
| Microtia | Point prevalence | 1-5 / 10 000 | United States | US | Unspecified |
| Microtia | Prevalence at birth | 1-5 / 10 000 | United States | US | Exact |
| Microtia | Point prevalence | 1-5 / 10 000 | United States | US | Exact |
| Microtia | Point prevalence | 1-5 / 10 000 | United States | US | Exact |
Showing 5 of 51 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Microtia | 83463 | Exact | Orphanet Rare Disease Ontology (ORDO) |
| Microtia | 83463 | Exact | Orphadata Science knowledge files, Product 1 |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: serious adverse events in this condition's trials and sub-conditions in mesh.