Organization (Industry)
4SC AG
ClinicalTrials.gov lists 4SC AG as lead sponsor of 13 trials. It has 7 active development programs and 3 approved assets.
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Trials started per year with this organization as sponsor or collaborator, 1990 onward. The series also counts trials where the organization is a collaborator; the lead-sponsor trial count does not.
2026 is partial: 0 registered with a 2026 start date. The dashed outline is the pace from the 0 registered with a start date through September, planned starts included, not adjusted; not a forecast. No forecast is made for this organization: it averages 0.4 trial starts a year over the five years to September, under the 5 a year the method needs.
Logo 4SC AG, via Wikimedia Commons, Public domain. Shown to identify the organization; it may be a registered trademark.
This page covers 4SC AG: 13 lead-sponsored trials and 2 legal-entity registrations.
Disease areas (23)
Shown in this order: most trials first.
| Disease area | Trials |
|---|---|
| Lymphoma | 5 |
| Carcinoma, Merkel Cell | 2 |
| Carcinoma, Neuroendocrine | 2 |
| Leukemia, Myeloid, Acute | 2 |
| Lymphoma, Non-Hodgkin | 2 |
Showing 5 of 23 disease areas.
Trials by start year as sponsor or collaborator (8)
Shown in this order: most recent first. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Show the table of trials by start year as sponsor or collaborator
| Year | Trials started |
|---|---|
| 2021 | 3 |
| 2020 | 2 |
| 2019 | 1 |
| 2017 | 1 |
| 2016 | 1 |
| 2011 | 2 |
| 2010 | 2 |
| 2009 | 4 |
Recruitment duration, a model prediction: none of the 13 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
Active development programs (7)
Shown in this order: max phase, then active trials.
| Drug | Disease area | Max phase | Trials |
|---|---|---|---|
| domatinostat in combination with avelumab | Carcinoma, Merkel Cell | Phase 2 | 2 |
| domatinostat in combination with avelumab | Carcinoma, Neuroendocrine | Phase 2 | 2 |
| Resminostat | Lymphoma | Phase 2 | 2 |
| Resminostat | Lymphoma, Non-Hodgkin | Phase 2 | 1 |
| Resminostat | Mycosis Fungoides | Phase 2 | 1 |
Showing 5 of 7 active programs.
Approved assets (3)
Shown in this order: max phase first.
| Drug | Trials |
|---|---|
| Folic (or folinic) acid | 1 |
| Sorafenib | 1 |
| METHOTREXATE | 1 |
Sponsor delivery record (1)
Enrollment hit target: the share of this sponsor's lead-sponsored trials whose actual enrollment reached the planned enrollment. On time: the share whose actual primary completion date was no later than the planned date. Each share counts only trials where we observed an estimated figure before the actual one, and n is that number of trials. Below 5 trials the count is shown as a fraction, not a percentage.
| Enrollment | Timeline |
|---|---|
| 2 of 3 hit target (n=3) | 1 of 3 on time (n=3) |
Journals published in (6)
Shown in this order: most published in first.
| Journal | Publications |
|---|---|
| The Cochrane database of systematic reviews | 2 |
| Drugs in R&D | 1 |
| ESMO open | 1 |
| Journal of Crohn's & colitis | 1 |
| Journal of hepatology | 1 |
Showing 5 of 6 journals.
US granted patents (1)
Patents are not classified by disease area in the source, so this is the organization's overall portfolio, not a split by disease.
| US patents granted | Granted in the last 5 years | Most recent grant |
|---|---|---|
| 52 | 1 | 2025-04-29 |
Organization relationships (2)
Shown in this order: most evidence first.
| Related organization | Relationship | Evidence |
|---|---|---|
| The Netherlands Cancer Institute | Co sponsors trial with | 1 |
| Merck KGaA, Darmstadt, Germany | Co sponsors trial with | 1 |
Latest dated events (68)
Shown in this order: newest first.
| Date | Event | Source |
|---|---|---|
| 2025-04-29 | Patent granted | Granted US patents (PatentsView / USPTO) |
| 2021-11-01 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2021-10-12 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2021-08-23 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2020-11-03 | Patent granted | Granted US patents (PatentsView / USPTO) |
Showing 5 of 68 events.
Biomarker capability evidence (50)
Shown in this order: tier desc, then gene symbol.
| Gene | Role | Evidence |
|---|---|---|
| EGFR | Trial sponsor | Named in trial inclusion criteria |
| F2 | Trial collaborator | Named in trial inclusion criteria |
| IFNG | Trial collaborator | Named in trial inclusion criteria |
| MCC | Trial sponsor | Named in trial inclusion criteria |
| MCC | Trial sponsor | Named in trial inclusion criteria |
Showing 5 of 50 evidence rows.
Not on this page
Checked, with nothing recorded for this organization: companies grouped under this page, related companies not grouped here, sec-reported annual financials, financing and grant events, fda warning letters, fda untitled letters, fda inspection record, fda recalls, fda import refusals, manufacturing and distribution sites, climate targets, as filed, workforce and board diversity, as filed, clia clinical laboratory certificates, and biomarkers this organization publishes on.