Organization (Industry)
IMMUNOCORE HOLDINGS PLC
ClinicalTrials.gov lists IMMUNOCORE HOLDINGS PLC as lead sponsor of 15 trials. It has 24 active development programs and 6 approved assets.
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Trials started per year with this organization as sponsor or collaborator, 1990 onward. The series also counts trials where the organization is a collaborator; the lead-sponsor trial count does not.
2026 is partial: 2 registered with a 2026 start date. The dashed outline is the pace from the 1 registered with a start date through September, planned starts included, not adjusted; not a forecast. No forecast is made for this organization: it averages 2.0 trial starts a year over the five years to September, under the 5 a year the method needs.
This page covers IMMUNOCORE HOLDINGS PLC: 15 lead-sponsored trials and 4 legal-entity registrations.
Disease areas (11)
Shown in this order: most trials first.
| Disease area | Trials |
|---|---|
| Melanoma | 13 |
| Uveal Melanoma | 10 |
| Cytokine Release Syndrome | 1 |
| Diabetes Mellitus | 1 |
| Diabetes Mellitus, Type 1 | 1 |
Showing 5 of 11 disease areas.
Trials by start year as sponsor or collaborator (11)
Shown in this order: most recent first. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Show the table of trials by start year as sponsor or collaborator
| Year | Trials started |
|---|---|
| 2026 (partial year) | 2 |
| 2025 | 3 |
| 2024 | 4 |
| 2022 | 2 |
| 2020 | 2 |
| 2019 | 1 |
| 2018 | 1 |
| 2017 | 2 |
| 2016 | 1 |
| 2015 | 1 |
Showing 10 of 11 years.
Recruitment duration, a model prediction: 3 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
Active development programs (24)
Shown in this order: max phase, then active trials.
| Drug | Disease area | Max phase | Trials |
|---|---|---|---|
| Tebentafusp | Melanoma | Phase 3 | 7 |
| Investigators Choice | Melanoma | Phase 3 | 1 |
| Investigators Choice | Nevus | Phase 3 | 1 |
| Investigators Choice | Nevus, Pigmented | Phase 3 | 1 |
| Tebentafusp with Pembrolizumab | Melanoma | Phase 3 | 1 |
Showing 5 of 24 active programs.
Approved assets (6)
Shown in this order: max phase first.
| Drug | Trials |
|---|---|
| Tebentafusp | 7 |
| NIVOLUMAB | 1 |
| IPILIMUMAB | 1 |
| Dacarbazine | 1 |
| PEMBROLIZUMAB | 1 |
Showing 5 of 6 approved assets.
Sponsor delivery record (1)
Enrollment hit target: the share of this sponsor's lead-sponsored trials whose actual enrollment reached the planned enrollment. On time: the share whose actual primary completion date was no later than the planned date. Each share counts only trials where we observed an estimated figure before the actual one, and n is that number of trials. Below 5 trials the count is shown as a fraction, not a percentage.
| Enrollment | Timeline |
|---|---|
| 25% hit target (n=8) | 20% on time (n=5) |
Journals published in (4)
Shown in this order: most published in first.
| Journal | Publications |
|---|---|
| The New England journal of medicine | 2 |
| Cell reports. Medicine | 1 |
| Journal for immunotherapy of cancer | 1 |
| Nature medicine | 1 |
US granted patents (1)
Patents are not classified by disease area in the source, so this is the organization's overall portfolio, not a split by disease.
| US patents granted | Granted in the last 5 years | Most recent grant |
|---|---|---|
| 47 | 14 | 2025-01-14 |
SEC-reported annual financials (9)
Shown in this order: newest fiscal year first; SEC EDGAR XBRL companyfacts, USD as reported.
| Fiscal year | Revenue (USD) | Net income (USD) | R&D (USD) |
|---|---|---|---|
| 2025 | 400,016,000 | -35,514,000 | 274,869,000 |
| 2024 | 310,202,000 | -51,087,000 | 222,151,000 |
| 2023 | 249,428,000 | -55,287,000 | 163,545,000 |
| 2022 | 174,361,000 | -52,543,000 | 101,921,000 |
| 2021 | 4,078,000 | -180,029,000 | 100,248,000 |
| 2020 | 38,613,346 | -95,004,938 | 95,923,021 |
| 2019 | 32,836,787 | -132,952,594 | 127,912,392 |
| 2018 | 31,364,214 | -94,978,383 | 110,816,954 |
| 2017 | not reported | not reported | not reported |
Financing and grant events (22)
Shown in this order: most recent first.
| Date | Round type | Amount (USD) | Source |
|---|---|---|---|
| 2025-03-17 | Follow-on offering | not disclosed | Edgar offerings |
| 2025-03-17 | Debt financing | not disclosed | Sec extracted |
| 2024-11-08 | Debt financing | not disclosed | Sec extracted |
| 2024-04-05 | Other financing | not disclosed | Edgar offerings |
| 2024-04-05 | Registered direct | not disclosed | Sec extracted |
Showing 5 of 22 events.
Climate targets, as filed (1)
| Reporting year | Net-zero target |
|---|---|
| 2025 | not disclosed |
Workforce and board diversity, as filed (1)
| Reporting year | Workforce % women | Board % women |
|---|---|---|
| 2025 | not disclosed | not disclosed |
Organization relationships (8)
Shown in this order: most evidence first.
| Related organization | Relationship | Evidence |
|---|---|---|
| University of California System | Co sponsors trial with | 1 |
| Thomas Jefferson University | Co sponsors trial with | 1 |
| Northwell Health | Co sponsors trial with | 1 |
| University of Miami | Co sponsors trial with | 1 |
| University of Oxford | Co sponsors trial with | 1 |
Showing 5 of 8 relationships.
Latest dated events (89)
Shown in this order: newest first.
| Date | Event | Source |
|---|---|---|
| 2026-11 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2026-04 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2025-09-05 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2025-08-18 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2025-03-17 | Follow-on offering | Funding rounds and grants (NIH RePORTER + SEC EDGAR) |
Showing 5 of 89 events.
Biomarker capability evidence (82)
Shown in this order: tier desc, then gene symbol.
| Gene | Role | Evidence |
|---|---|---|
| BRAF | Trial sponsor | Named in trial inclusion criteria |
| BRAF | Trial sponsor | Named in trial inclusion criteria |
| CTAG1A; CTAG1B | Trial sponsor | Named in trial inclusion criteria |
| CTLA4 | Trial sponsor | Named in trial inclusion criteria |
| CTLA4 | Trial collaborator | Named in trial inclusion criteria |
Showing 5 of 82 evidence rows.
Not on this page
Checked, with nothing recorded for this organization: companies grouped under this page, related companies not grouped here, fda warning letters, fda untitled letters, fda inspection record, fda recalls, fda import refusals, manufacturing and distribution sites, clia clinical laboratory certificates, and biomarkers this organization publishes on.