Organization (Other)
Rothman Institute Orthopaedics
ClinicalTrials.gov lists Rothman Institute Orthopaedics as lead sponsor of 119 trials. It has 12 active development programs and 35 approved assets.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials started per year with this organization as sponsor or collaborator, 1990 onward. The series also counts trials where the organization is a collaborator; the lead-sponsor trial count does not.
2026 is partial: 1 registered with a 2026 start date. The dashed outline is the pace from the 1 registered with a start date through September, planned starts included, not adjusted; not a forecast. No forecast is made for this organization: it averages 4.8 trial starts a year over the five years to September, under the 5 a year the method needs.
This page covers Rothman Institute Orthopaedics: 119 lead-sponsored trials and 0 legal-entity registrations.
Disease areas (37)
Shown in this order: most trials first.
| Disease area | Trials |
|---|---|
| Pain | 26 |
| Postoperative Pain | 21 |
| Osteoarthritis | 14 |
| Rotator Cuff Injuries | 9 |
| Fractures, Bone | 8 |
Showing 5 of 37 disease areas.
Trials by start year as sponsor or collaborator (20)
Shown in this order: most recent first. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Show the table of trials by start year as sponsor or collaborator
| Year | Trials started |
|---|---|
| 2026 (partial year) | 1 |
| 2025 | 1 |
| 2024 | 7 |
| 2023 | 7 |
| 2022 | 5 |
| 2021 | 10 |
| 2020 | 15 |
| 2019 | 10 |
| 2018 | 11 |
| 2017 | 14 |
Showing 10 of 20 years.
Prediction, not a registry value: median of 33 months from start to primary completion across 10 trials still running at the 2026-10-09 snapshot; registered median of 18 months across 31 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
Active development programs (12)
Shown in this order: max phase, then active trials.
| Drug | Disease area | Max phase | Trials |
|---|---|---|---|
| Acetaminophen | Pain | Phase 3 | 2 |
| Acetaminophen | Postoperative Pain | Phase 3 | 2 |
| Naproxen | Postoperative Pain | Phase 3 | 1 |
| Naproxen | Pain | Phase 3 | 1 |
| Bupivacaine 0.5% Injectable Solution | Pain | Phase 3 | 2 |
Showing 5 of 12 active programs.
Approved assets (35)
Shown in this order: max phase first.
| Drug | Trials |
|---|---|
| +/- Bupivacaine HCl | 6 |
| DEXAMETHASONE | 4 |
| OxyCODONE 5 Mg (milligram) Oral Tablet | 3 |
| Ketorolac | 3 |
| Naproxen 500 Mg | 3 |
Showing 5 of 35 approved assets.
Sponsor delivery record (1)
Enrollment hit target: the share of this sponsor's lead-sponsored trials whose actual enrollment reached the planned enrollment. On time: the share whose actual primary completion date was no later than the planned date. Each share counts only trials where we observed an estimated figure before the actual one, and n is that number of trials. Below 5 trials the count is shown as a fraction, not a percentage.
| Enrollment | Timeline |
|---|---|
| 1 of 2 hit target (n=2) | 20% on time (n=5) |
Journals published in (26)
Shown in this order: most published in first.
| Journal | Publications |
|---|---|
| The Journal of arthroplasty | 4 |
| Clinical orthopaedics and related research | 3 |
| Regional anesthesia and pain medicine | 3 |
| Spine | 3 |
| Foot & ankle international | 2 |
Showing 5 of 26 journals.
Organization relationships (2)
Shown in this order: most evidence first.
| Related organization | Relationship | Evidence |
|---|---|---|
| Thomas Jefferson University | Co sponsors trial with | 1 |
| Lantheus Medical Imaging (United States) | Co sponsors trial with | 1 |
Latest dated events (117)
Shown in this order: newest first.
| Date | Event | Source |
|---|---|---|
| 2026-07-21 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2025-03-25 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2024-11-01 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2024-09-16 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2024-08-26 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
Showing 5 of 117 events.
Biomarker capability evidence (12)
Shown in this order: tier desc, then gene symbol.
| Gene | Role | Evidence |
|---|---|---|
| CRP | Trial sponsor | Named in trial inclusion criteria |
| PAOX | Trial sponsor | Named in trial inclusion criteria |
| ALB | Trial sponsor | Named in trial exclusion criteria |
| EPO | Trial sponsor | Named in trial exclusion criteria |
| SLA | Trial sponsor | Named in trial exclusion criteria |
Showing 5 of 12 evidence rows.
Biomarkers this organization publishes on (3)
Shown in this order: most publications first.
Not on this page
Checked, with nothing recorded for this organization: companies grouped under this page, related companies not grouped here, us granted patents, sec-reported annual financials, financing and grant events, fda warning letters, fda untitled letters, fda inspection record, fda recalls, fda import refusals, manufacturing and distribution sites, climate targets, as filed, workforce and board diversity, as filed, and clia clinical laboratory certificates.