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Clinical trial

A Phase 1, Open-label, Dose-escalation, Safety and Pharmacokinetic Study of CDX-1127 in Patients With Selected Refractory or Relapsed Hematologic Malignancies or Solid Tumors

NCT01460134 is registered in ClinicalTrials.gov with Celldex Therapeutics as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase 1, Open-label, Dose-escalation, Safety and Pharmacokinetic Study of CDX-1127 in Patients With Selected Refractory or Relapsed Hematologic Malignancies or Solid Tumors
Lead sponsor
Celldex Therapeutics
Phase
Phase 1
Overall status
Completed
Start date
October 31, 2011
Completion date
October 16, 2017
Enrollment
90 (actual)
Sites
10

Conditions

As the registry lists them; a condition with its own page is linked.

any t-cell malignancy, burkett's lymphoma, cd27 expressing b-cell malignancies for example hodgkin's lymphoma, chronic lymphocytic leukemia, colorectal adenocarcinoma, non-small cell lung cancer), hormone-refractory prostate adenocarcinoma, ovarian cancer, mantle cell lymphoma, marginal zone b cell lymphoma), primary lymphoma of the central nervous system, solid tumors (metastatic melanoma, renal (clear) cell carcinoma