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Clinical trial

A Randomized, Double-Blind Pilot Study of N-Acetylcysteine Mucoadherent Rinse Versus Placebo for Thickened Secretions and Mucositis Secondary to Chemoradiotherapy in the Management of Head and Neck Malignancies

NCT02123511 is registered in ClinicalTrials.gov with Mayo Clinic as lead sponsor.

NCT NCT02123511
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Registry record

As filed in ClinicalTrials.gov.

Title
A Randomized, Double-Blind Pilot Study of N-Acetylcysteine Mucoadherent Rinse Versus Placebo for Thickened Secretions and Mucositis Secondary to Chemoradiotherapy in the Management of Head and Neck Malignancies
Lead sponsor
Mayo Clinic
Phase
Phase 2
Overall status
Completed
Start date
April 30, 2014
Completion date
July 2, 2018
Enrollment
34 (actual)
Sites
5

Conditions

As the registry lists them; a condition with its own page is linked.

mucositis, oral complications, recurrent adenoid cystic carcinoma of the oral cavity, recurrent basal cell carcinoma of the lip, recurrent lymphoepithelioma of the nasopharynx, recurrent lymphoepithelioma of the oropharynx, recurrent mucoepidermoid carcinoma of the oral cavity, recurrent salivary gland cancer, recurrent squamous cell carcinoma of the larynx, recurrent squamous cell carcinoma of the lip and oral cavity, recurrent squamous cell carcinoma of the nasopharynx, recurrent squamous cell carcinoma of the oropharynx, recurrent verrucous carcinoma of the larynx, recurrent verrucous carcinoma of the oral cavity, stage i adenoid cystic carcinoma of the oral cavity, stage i basal cell carcinoma of the lip, stage i lymphoepithelioma of the nasopharynx, stage i lymphoepithelioma of the oropharynx, stage i mucoepidermoid carcinoma of the oral cavity, stage i salivary gland cancer, stage i squamous cell carcinoma of the larynx, stage i squamous cell carcinoma of the lip and oral cavity, stage i squamous cell carcinoma of the nasopharynx, stage i squamous cell carcinoma of the oropharynx, stage i verrucous carcinoma of the larynx, stage i verrucous carcinoma of the oral cavity, stage ii adenoid cystic carcinoma of the oral cavity, stage ii basal cell carcinoma of the lip, stage ii lymphoepithelioma of the nasopharynx, stage ii lymphoepithelioma of the oropharynx, stage ii mucoepidermoid carcinoma of the oral cavity, stage ii salivary gland cancer, stage ii squamous cell carcinoma of the larynx, stage ii squamous cell carcinoma of the lip and oral cavity, stage ii squamous cell carcinoma of the nasopharynx, stage ii squamous cell carcinoma of the oropharynx, stage ii verrucous carcinoma of the larynx, stage ii verrucous carcinoma of the oral cavity, stage iii adenoid cystic carcinoma of the oral cavity, stage iii basal cell carcinoma of the lip, stage iii lymphoepithelioma of the nasopharynx, stage iii lymphoepithelioma of the oropharynx, stage iii mucoepidermoid carcinoma of the oral cavity, stage iii salivary gland cancer, stage iii squamous cell carcinoma of the larynx, stage iii squamous cell carcinoma of the lip and oral cavity, stage iii squamous cell carcinoma of the nasopharynx, stage iii squamous cell carcinoma of the oropharynx, stage iii verrucous carcinoma of the larynx, stage iii verrucous carcinoma of the oral cavity, stage iv lymphoepithelioma of the nasopharynx, stage iv squamous cell carcinoma of the nasopharynx, stage iva adenoid cystic carcinoma of the oral cavity, stage iva basal cell carcinoma of the lip, stage iva lymphoepithelioma of the oropharynx, stage iva mucoepidermoid carcinoma of the oral cavity, stage iva salivary gland cancer, stage iva squamous cell carcinoma of the larynx, stage iva squamous cell carcinoma of the lip and oral cavity, stage iva squamous cell carcinoma of the oropharynx, stage iva verrucous carcinoma of the larynx, stage iva verrucous carcinoma of the oral cavity, stage ivb adenoid cystic carcinoma of the oral cavity, stage ivb basal cell carcinoma of the lip, stage ivb lymphoepithelioma of the oropharynx, stage ivb mucoepidermoid carcinoma of the oral cavity, stage ivb salivary gland cancer, stage ivb squamous cell carcinoma of the larynx, stage ivb squamous cell carcinoma of the lip and oral cavity, stage ivb squamous cell carcinoma of the oropharynx, stage ivb verrucous carcinoma of the larynx, stage ivb verrucous carcinoma of the oral cavity, stage ivc adenoid cystic carcinoma of the oral cavity, stage ivc basal cell carcinoma of the lip, stage ivc lymphoepithelioma of the oropharynx, stage ivc mucoepidermoid carcinoma of the oral cavity, stage ivc salivary gland cancer, stage ivc squamous cell carcinoma of the larynx, stage ivc squamous cell carcinoma of the lip and oral cavity, stage ivc squamous cell carcinoma of the oropharynx, stage ivc verrucous carcinoma of the larynx, stage ivc verrucous carcinoma of the oral cavity, tongue cancer