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Clinical trial

Pazopanib Neoadjuvant Trial in Non-Rhabdomyosarcoma Soft Tissue Sarcomas (PAZNTIS): A Phase II/III Randomized Trial of Preoperative Chemoradiation or Preoperative Radiation Plus or Minus Pazopanib (NSC# 737754)

NCT02180867 is registered in ClinicalTrials.gov with National Cancer Institute (NCI) as lead sponsor.

NCT NCT02180867
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Registry record

As filed in ClinicalTrials.gov.

Title
Pazopanib Neoadjuvant Trial in Non-Rhabdomyosarcoma Soft Tissue Sarcomas (PAZNTIS): A Phase II/III Randomized Trial of Preoperative Chemoradiation or Preoperative Radiation Plus or Minus Pazopanib (NSC# 737754)
Lead sponsor
National Cancer Institute (NCI)
Phase
Phase 2/3
Overall status
Completed
Start date
August 12, 2014
Completion date
March 31, 2026
Enrollment
140 (actual)
Sites
381

Conditions

As the registry lists them; a condition with its own page is linked.

alveolar soft part sarcoma, angiomatoid fibrous histiocytoma, atypical fibroxanthoma, clear cell sarcoma of soft tissue, epithelioid malignant peripheral nerve sheath tumor, epithelioid sarcoma, extraskeletal myxoid chondrosarcoma, extraskeletal osteosarcoma, fibrohistiocytic neoplasm, fibrosarcoma, inflammatory myofibroblastic tumor, intimal sarcoma, leiomyosarcoma, liposarcoma, liver embryonal sarcoma, low grade fibromyxoid sarcoma, low grade myofibroblastic sarcoma, malignant peripheral nerve sheath tumor, malignant skin granular cell tumor, malignant triton tumor, mesenchymal chondrosarcoma, myxofibrosarcoma, myxoid chondrosarcoma, myxoinflammatory fibroblastic sarcoma, nerve sheath neoplasm, pecoma, pericytic neoplasm, plexiform fibrohistiocytic tumor, sclerosing epithelioid fibrosarcoma, skin glomus tumor, stage ib soft tissue sarcoma ajcc v7, stage iib soft tissue sarcoma ajcc v7, stage iii soft tissue sarcoma ajcc v7, stage iv soft tissue sarcoma ajcc v7, synovial sarcoma, undifferentiated high grade pleomorphic sarcoma of bone