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Clinical trial

A Randomized Phase II Trial of Cisplatin With or Without Wee1 Kinase Inhibitor AZD1775 (MK-1775) for First-line Treatment of Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck (RM-SCCHN)

NCT02196168 is registered in ClinicalTrials.gov with National Cancer Institute (NCI) as lead sponsor.

NCT NCT02196168
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Registry record

As filed in ClinicalTrials.gov.

Title
A Randomized Phase II Trial of Cisplatin With or Without Wee1 Kinase Inhibitor AZD1775 (MK-1775) for First-line Treatment of Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck (RM-SCCHN)
Lead sponsor
National Cancer Institute (NCI)
Phase
Phase 2
Overall status
Terminated
Start date
March 31, 2014
Completion date
April 30, 2016
Enrollment
6 (actual)
Sites
3

Conditions

As the registry lists them; a condition with its own page is linked.

recurrent hypopharyngeal squamous cell carcinoma, recurrent laryngeal squamous cell carcinoma, recurrent laryngeal verrucous carcinoma, recurrent lip and oral cavity squamous cell carcinoma, recurrent metastatic squamous cell carcinoma in the neck with occult primary, recurrent nasal cavity and paranasal sinus squamous cell carcinoma, recurrent oral cavity verrucous carcinoma, recurrent oropharyngeal squamous cell carcinoma, squamous cell carcinoma metastatic in the neck with occult primary, stage iv hypopharyngeal squamous cell carcinoma, stage iva laryngeal squamous cell carcinoma, stage iva laryngeal verrucous carcinoma, stage iva lip and oral cavity squamous cell carcinoma, stage iva nasal cavity and paranasal sinus squamous cell carcinoma, stage iva oral cavity verrucous carcinoma, stage iva oropharyngeal squamous cell carcinoma, stage ivb laryngeal squamous cell carcinoma, stage ivb laryngeal verrucous carcinoma, stage ivb lip and oral cavity squamous cell carcinoma, stage ivb nasal cavity and paranasal sinus squamous cell carcinoma, stage ivb oral cavity verrucous carcinoma, stage ivb oropharyngeal squamous cell carcinoma, stage ivc laryngeal squamous cell carcinoma, stage ivc laryngeal verrucous carcinoma, stage ivc lip and oral cavity squamous cell carcinoma, stage ivc nasal cavity and paranasal sinus squamous cell carcinoma, stage ivc oral cavity verrucous carcinoma, stage ivc oropharyngeal squamous cell carcinoma, tongue carcinoma