Clinical trial
A Phase 1b and 2a Study to Assess Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of CGT9486 as a Single Agent and in Combination With PLX3397 or Sunitinib (Sutent®) in Patients With Advanced Solid Tumors and Patients With Locally Advanced, Unresectable, or Metastatic Gastrointestinal Stromal Tumor (GIST) Who Have Been Previously Treated With Imatinib Mesylate/KIT-Directed Tyrosine Kinase Inhibitor (TKI) Therapy
NCT02401815 is registered in ClinicalTrials.gov with Cogent Biosciences, Inc. as lead sponsor.
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Registry record
As filed in ClinicalTrials.gov.
- Title
- A Phase 1b and 2a Study to Assess Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of CGT9486 as a Single Agent and in Combination With PLX3397 or Sunitinib (Sutent®) in Patients With Advanced Solid Tumors and Patients With Locally Advanced, Unresectable, or Metastatic Gastrointestinal Stromal Tumor (GIST) Who Have Been Previously Treated With Imatinib Mesylate/KIT-Directed Tyrosine Kinase Inhibitor (TKI) Therapy
- Lead sponsor
- Cogent Biosciences, Inc.
- Phase
- Phase 1/2
- Overall status
- Completed
- Start date
- March 6, 2015
- Completion date
- May 11, 2020
- Enrollment
- 51 (actual)
- Sites
- 6
Conditions
As the registry lists them; a condition with its own page is linked.