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Clinical trial

A Safety, Pharmacokinetic and Efficacy Study of a y-Secretase Inhibitor, Nirogacestat (PF-03084014), in Children and Adolescents With Progressive, Surgically Unresectable Desmoid Tumors

NCT04195399 is registered in ClinicalTrials.gov with Children's Oncology Group as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Safety, Pharmacokinetic and Efficacy Study of a y-Secretase Inhibitor, Nirogacestat (PF-03084014), in Children and Adolescents With Progressive, Surgically Unresectable Desmoid Tumors
Lead sponsor
Children's Oncology Group
Phase
Phase 2
Overall status
Active, not recruiting
Start date
October 7, 2020
Completion date
December 31, 2032
Enrollment
31 (actual)
Sites
98

Conditions

As the registry lists them; a condition with its own page is linked.

desmoid fibromatosis, recurrent desmoid fibromatosis, unresectable desmoid fibromatosis