Condition (MeSH)
Desmoid Tumors
ClinicalTrials.gov lists 67 trials for Desmoid Tumors or a narrower condition beneath it. Children's Oncology Group has the most among industry and government lead sponsors, with 7.
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Trials per phase
1 more section with rows
67 of the 67 trials are tagged with Desmoid Tumors itself; the rest are tagged with a narrower condition beneath it.
When did Desmoid Tumors trials start? (24)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 7
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 2 |
| 2025 | 4 |
| 2024 | 7 |
| 2023 | 3 |
| 2022 | 2 |
| 2021 | 4 |
| 2020 | 5 |
| 2019 | 3 |
| 2018 | 2 |
| 2017 | 3 |
Showing 10 of 24 earlier years.
No forecast is made for this condition: it averages 3.8 trial starts a year over the five years to September, under the 5 a year the method needs.
Prediction, not a registry value: median of 36 months from start to primary completion across 7 trials still running at the 2026-10-09 snapshot; registered median of 51 months across 35 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Desmoid Tumors trials in? (9)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 9 |
| Phase 1/2 | 6 |
| Phase 2 | 16 |
| Phase 2/3 | 1 |
| Phase 3 | 4 |
| Phase 4 | 1 |
| Not applicable | 9 |
| Observational | 19 |
| Expanded access | 2 |
How many Desmoid Tumors trials are recruiting? (10)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 2 |
| Recruiting | 14 |
| Enrolling by invitation | 1 |
| Active, not recruiting | 7 |
| Available | 1 |
Showing 5 of 10 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Desmoid Tumors trials? (4)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Children's Oncology Group | 7 |
| National Cancer Institute (NCI) | 4 |
| SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany | 4 |
| Eisai Co., Ltd. | 1 |
Which drugs are being tested for Desmoid Tumors? (5)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Nirogacestat | 8 |
| NIVOLUMAB | 3 |
| Tegavivint | 2 |
| Toremifene | 2 |
| Imatinib | 2 |
Interventions as named in the registry (10)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Cryoablation | 3 |
| Doxorubicine | 2 |
| Blood Sampling | 2 |
| Vinblastin | 1 |
| vactosertib/imatinib combination | 1 |
Showing 5 of 10 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Desmoid Tumors trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Abdominal pain | 5 | 4 |
| Nausea | 4 | 2 |
| Sepsis | 4 | 2 |
| Hypertension | 3 | 1 |
| Premature menopause | 3 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Desmoid Tumors? (42)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
Showing 5 of 42 publications.
Prevalence (3)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Desmoid tumor | Annual incidence | 1-9 / 1 000 000 | Finland | Not stated | Unspecified |
| Desmoid tumor | Annual incidence | 1-9 / 1 000 000 | Europe | Not stated | Unspecified |
| Desmoid tumor | Point prevalence | Unknown | Worldwide | Not stated | Unspecified |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: rare-disease identity and sub-conditions in mesh.