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Clinical trial

A Phase 1 Trial of the ATR Inhibitor BAY 1895344 in Combination With Cisplatin and With Cisplatin Plus Gemcitabine in Advanced Solid Tumors With an Emphasis on Urothelial Carcinoma

NCT04491942 is registered in ClinicalTrials.gov with National Cancer Institute (NCI) as lead sponsor.

NCT NCT04491942
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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase 1 Trial of the ATR Inhibitor BAY 1895344 in Combination With Cisplatin and With Cisplatin Plus Gemcitabine in Advanced Solid Tumors With an Emphasis on Urothelial Carcinoma
Lead sponsor
National Cancer Institute (NCI)
Phase
Phase 1
Overall status
Active, not recruiting
Start date
August 25, 2021
Completion date
June 30, 2027
Enrollment
74 (estimated)
Sites
8

Conditions

As the registry lists them; a condition with its own page is linked.

advanced bile duct carcinoma, advanced breast carcinoma, advanced cervical carcinoma, advanced endometrial carcinoma, advanced esophageal carcinoma, advanced gastric carcinoma, advanced head and neck carcinoma, advanced lung non-small cell carcinoma, advanced lung small cell carcinoma, advanced malignant solid neoplasm, advanced ovarian carcinoma, advanced penile carcinoma, advanced pleural malignant mesothelioma, advanced urothelial carcinoma, anatomic stage iii breast cancer ajcc v8, anatomic stage iv breast cancer ajcc v8, clinical stage iii gastric cancer ajcc v8, clinical stage iv gastric cancer ajcc v8, stage iii cervical cancer ajcc v8, stage iii distal bile duct cancer ajcc v8, stage iii intrahepatic bile duct cancer ajcc v8, stage iii lung cancer ajcc v8, stage iii ovarian cancer ajcc v8, stage iii penile cancer ajcc v8, stage iii pleural diffuse malignant mesothelioma ajcc v8, stage iv cervical cancer ajcc v8, stage iv distal bile duct cancer ajcc v8, stage iv intrahepatic bile duct cancer ajcc v8, stage iv lung cancer ajcc v8, stage iv ovarian cancer ajcc v8, stage iv penile cancer ajcc v8, stage iv pleural diffuse malignant mesothelioma ajcc v8, triple-negative breast carcinoma, unresectable urothelial carcinoma