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Clinical trial

Open-Label Phase 1b/2 Study of Cetuximab Administered in Combination With LY3214996 (ERK 1/2 Inhibitor) or Cetuximab in Combination With LY3214996 and Abemaciclib in Patients With Metastatic, Anti-EGFR-Refractory Colorectal Cancer

NCT04616183 is registered in ClinicalTrials.gov with M.D. Anderson Cancer Center as lead sponsor.

NCT NCT04616183
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Registry record

As filed in ClinicalTrials.gov.

Title
Open-Label Phase 1b/2 Study of Cetuximab Administered in Combination With LY3214996 (ERK 1/2 Inhibitor) or Cetuximab in Combination With LY3214996 and Abemaciclib in Patients With Metastatic, Anti-EGFR-Refractory Colorectal Cancer
Lead sponsor
M.D. Anderson Cancer Center
Phase
Phase 1/2
Overall status
Active, not recruiting
Start date
December 2, 2020
Completion date
December 31, 2028
Enrollment
46 (actual)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

metastatic colon adenocarcinoma, metastatic colorectal carcinoma, metastatic rectal adenocarcinoma, recurrent colorectal carcinoma, stage iii colon cancer ajcc v8, stage iii colorectal cancer ajcc v8, stage iii rectal cancer ajcc v8, stage iiia colon cancer ajcc v8, stage iiia colorectal cancer ajcc v8, stage iiia rectal cancer ajcc v8, stage iiib colon cancer ajcc v8, stage iiib colorectal cancer ajcc v8, stage iiib rectal cancer ajcc v8, stage iiic colon cancer ajcc v8, stage iiic colorectal cancer ajcc v8, stage iiic rectal cancer ajcc v8, stage iv colon cancer ajcc v8, stage iv colorectal cancer ajcc v8, stage iv rectal cancer ajcc v8, stage iva colon cancer ajcc v8, stage iva colorectal cancer ajcc v8, stage iva rectal cancer ajcc v8, stage ivb colon cancer ajcc v8, stage ivb colorectal cancer ajcc v8, stage ivb rectal cancer ajcc v8, stage ivc colon cancer ajcc v8, stage ivc colorectal cancer ajcc v8, stage ivc rectal cancer ajcc v8, unresectable colon adenocarcinoma, unresectable colorectal carcinoma, unresectable rectal adenocarcinoma