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Clinical trial

Phase 1/1B Study of DS-8201a in Combination With ATR Inhibition (AZD6738) in Advanced Solid Tumors With HER2 Expression (DASH Trial)

NCT04704661 is registered in ClinicalTrials.gov with National Cancer Institute (NCI) as lead sponsor.

NCT NCT04704661
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Registry record

As filed in ClinicalTrials.gov.

Title
Phase 1/1B Study of DS-8201a in Combination With ATR Inhibition (AZD6738) in Advanced Solid Tumors With HER2 Expression (DASH Trial)
Lead sponsor
National Cancer Institute (NCI)
Phase
Phase 1
Overall status
Active, not recruiting
Start date
August 9, 2021
Completion date
March 31, 2027
Enrollment
51 (estimated)
Sites
23

Conditions

As the registry lists them; a condition with its own page is linked.

advanced breast carcinoma, advanced colon carcinoma, advanced colorectal carcinoma, advanced endometrial carcinoma, advanced gastric carcinoma, advanced gastroesophageal junction adenocarcinoma, advanced malignant solid neoplasm, advanced salivary gland carcinoma, anatomic stage iii breast cancer ajcc v8, anatomic stage iv breast cancer ajcc v8, clinical stage iii gastric cancer ajcc v8, clinical stage iii gastroesophageal junction adenocarcinoma ajcc v8, clinical stage iv gastric cancer ajcc v8, clinical stage iv gastroesophageal junction adenocarcinoma ajcc v8, her2-positive breast carcinoma, malignant hepatobiliary neoplasm, metastatic breast carcinoma, metastatic colon carcinoma, metastatic colorectal carcinoma, metastatic endometrial carcinoma, metastatic gastric carcinoma, metastatic gastroesophageal junction adenocarcinoma, metastatic malignant solid neoplasm, metastatic salivary gland carcinoma, stage iii colon cancer ajcc v8, stage iii colorectal cancer ajcc v8, stage iii major salivary gland cancer ajcc v8, stage iii uterine corpus carcinoma or carcinosarcoma ajcc v8, stage iv colon cancer ajcc v8, stage iv colorectal cancer ajcc v8, stage iv major salivary gland cancer ajcc v8, stage iv uterine corpus carcinoma or carcinosarcoma ajcc v8, unresectable breast carcinoma, unresectable colon carcinoma, unresectable colorectal carcinoma, unresectable endometrial carcinoma, unresectable gastric carcinoma, unresectable gastroesophageal junction adenocarcinoma, unresectable malignant solid neoplasm, unresectable salivary gland carcinoma