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Condition (MeSH)

Carcinosarcoma

ClinicalTrials.gov lists 39 trials for Carcinosarcoma or a narrower condition beneath it. National Cancer Institute (NCI) has the most among industry and government lead sponsors, with 7.

MeSH D002296 Neoplasms Neoplasm C04
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Phase 1 Phase 1 7 Phase 1/2 Phase 1/2 3 Phase 2 Phase 2 18 Phase 3 Phase 3 4 Not applicable Not applicable 2 Observational Observational 4 Expanded access Expanded access 1 Phase 1 Phase 1 7 Phase 1/2 Phase 1/2 3 Phase 2 Phase 2 18 Phase 3 Phase 3 4 Not applicable Not applicable 2 Observational Observational 4 Expanded access Expanded access 1

Trials per phase

39 of the 39 trials are tagged with Carcinosarcoma itself; the rest are tagged with a narrower condition beneath it.

Get the Carcinosarcoma report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Carcinosarcoma trials start? (14)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 3
  • Not applicable
  • Observational

Top of scale: 6

2002: 1 trials (Phase 2 1) 2005: 1 trials (Phase 1 1) 2008: 1 trials (Phase 2 1) 2009: 1 trials (Phase 3 1) 2017: 4 trials (Phase 2 3, Phase 1 1) 2018: 6 trials (Observational 1, Phase 2 4, Phase 1/2 1) 2019: 6 trials (Observational 1, Phase 3 1, Phase 2 4) 2020: 4 trials (Not applicable 1, Phase 3 1, Phase 2 2) 2021: 3 trials (Observational 1, Phase 2 1, Phase 1 1) 2022: 3 trials (Phase 3 1, Phase 1/2 1, Phase 1 1) 2023: 2 trials (Phase 1 2) 2024: 4 trials (Observational 1, Phase 2 2, Phase 1/2 1) 2025: 1 trials (Phase 1 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 1
2025 1
2024 4
2023 2
2022 3
2021 3
2020 4
2019 6
2018 6
2017 4

No forecast is made for this condition: it averages 2.4 trial starts a year over the five years to September, under the 5 a year the method needs.

Prediction, not a registry value: median of 36 months from start to primary completion across 9 trials still running at the 2026-10-09 snapshot; registered median of 43 months across 21 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Carcinosarcoma trials in? (7)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 7
Phase 1/2 3
Phase 2 18
Phase 3 4
Not applicable 2
Observational 4
Expanded access 1

How many Carcinosarcoma trials are recruiting? (8)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 1
Recruiting 8
Active, not recruiting 9
Completed 8
Terminated 6

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Carcinosarcoma trials? (6)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Cancer Institute (NCI) 7
Leap Therapeutics, Inc. 2
Blueprint Medicines Corporation 1
Deciphera Pharmaceuticals, LLC 1
GOG Foundation 1

Which drugs are being tested for Carcinosarcoma? (7)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
(nab)-paclitaxel 8
NIVOLUMAB 5
PEMBROLIZUMAB 3
DURVALUMAB 2
Trastuzumab Deruxtecan 2

Interventions as named in the registry (8)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
or carboplatin 6
Arm A - Olaparib 3
Doxorubicine 2
AZD6738 / ceralasertib 2
Ifosfamid 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Carcinosarcoma trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Neutrophil count decreased 113 1
Anemia 100 4
White blood cell decreased 62 1
Hypertension 53 4
Neutrophils 44 1

Which publications cover Carcinosarcoma? (46)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.

Browse all condition evidence pages