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Clinical trial

A Phase 1 Study of the SHP2 Inhibitor BBP-398 (Formerly Known as IACS-15509) in Combination With the Programmed Death Receptor-1 Blocking Antibody Nivolumab in Patients With Advanced Non-Small Cell Lung Cancer With a KRAS Mutation

NCT05375084 is registered in ClinicalTrials.gov with Navire Pharma Inc., a BridgeBio company as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase 1 Study of the SHP2 Inhibitor BBP-398 (Formerly Known as IACS-15509) in Combination With the Programmed Death Receptor-1 Blocking Antibody Nivolumab in Patients With Advanced Non-Small Cell Lung Cancer With a KRAS Mutation
Lead sponsor
Navire Pharma Inc., a BridgeBio company
Phase
Phase 1
Overall status
Terminated
Start date
October 20, 2022
Completion date
July 15, 2024
Enrollment
21 (actual)
Sites
15

Conditions

As the registry lists them; a condition with its own page is linked.

non small cell lung cancer, solid tumor