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Clinical trial

A Phase Ib Study to Evaluate Safety and Persistence of ex Vivo Expanded Universal Donor NK Cells in Combination With IL-2 and TGFbeta Receptor I Inhibitor Vactosertib in Patients With Locally Advanced/Metastatic Colorectal Cancer, Gastric/Esophageal Cancer, and Relapsed/Refractory Hematologic Malignancies

NCT05400122 is registered in ClinicalTrials.gov with David Wald as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase Ib Study to Evaluate Safety and Persistence of ex Vivo Expanded Universal Donor NK Cells in Combination With IL-2 and TGFbeta Receptor I Inhibitor Vactosertib in Patients With Locally Advanced/Metastatic Colorectal Cancer, Gastric/Esophageal Cancer, and Relapsed/Refractory Hematologic Malignancies
Lead sponsor
David Wald
Phase
Phase 1
Overall status
Suspended
Start date
September 9, 2022
Completion date
June 1, 2027
Enrollment
12 (estimated)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

acute lymphoblastic leukemia, acute myeloid leukemia, chronic lymphocytic leukemia, chronic myeloid leukemia, colorectal cancer, esophageal cancer, esophagus cancer, gastric cancer, gastric cancer, metastatic, hematologic malignancy, hodgkin lymphoma, metastatic esophageal cancer, myelodysplastic syndromes, myeloproliferative syndrome, non hodgkin lymphoma, plasma cell myeloma, rectum cancer, unresectable esophageal cancer