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Clinical trial

A PHASE 2, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO INVESTIGATE THE EFFICACY, SAFETY AND TOLERABILITY OF PONSEGROMAB IN PATIENTS WITH CANCER, CACHEXIA, AND ELEVATED CONCENTRATIONS OF GDF-15, FOLLOWED BY AN OPTIONAL OPEN-LABEL TREATMENT PERIOD (PROACC -1)

NCT05546476 is registered in ClinicalTrials.gov with Pfizer as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A PHASE 2, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO INVESTIGATE THE EFFICACY, SAFETY AND TOLERABILITY OF PONSEGROMAB IN PATIENTS WITH CANCER, CACHEXIA, AND ELEVATED CONCENTRATIONS OF GDF-15, FOLLOWED BY AN OPTIONAL OPEN-LABEL TREATMENT PERIOD (PROACC -1)
Lead sponsor
Pfizer
Phase
Phase 2
Overall status
Completed
Start date
November 21, 2022
Completion date
April 23, 2025
Enrollment
187 (actual)
Sites
78

Conditions

As the registry lists them; a condition with its own page is linked.

cachexia, colorectal cancer, fatigue, loss of appetite, non-small cell lung cancer, pancreatic cancer