Clinical trial
A Phase 1, Open-Label, 4-Part, Fixed-Sequence Study to Assess the Effect of Itraconazole, a Strong CYP3A Inhibitor, the Effect of Fluconazole, a Moderate CYP3A/2C9 Inhibitor, the Effect of Rifampin, a Strong CYP3A Inducer, and the Effect of Rabeprazole, a Proton Pump Inhibitor on the Pharmacokinetics of HMPL-689 in Healthy Volunteers
NCT05602597 is registered in ClinicalTrials.gov with Hutchmed as lead sponsor.
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Registry record
As filed in ClinicalTrials.gov.
- Title
- A Phase 1, Open-Label, 4-Part, Fixed-Sequence Study to Assess the Effect of Itraconazole, a Strong CYP3A Inhibitor, the Effect of Fluconazole, a Moderate CYP3A/2C9 Inhibitor, the Effect of Rifampin, a Strong CYP3A Inducer, and the Effect of Rabeprazole, a Proton Pump Inhibitor on the Pharmacokinetics of HMPL-689 in Healthy Volunteers
- Lead sponsor
- Hutchmed
- Phase
- Phase 1
- Overall status
- Completed
- Start date
- June 1, 2022
- Completion date
- August 6, 2022
- Enrollment
- 59 (actual)
- Sites
- 1
Conditions
As the registry lists them; a condition with its own page is linked.
relapsed or refractory lymphoma