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Clinical trial

A First-in-Human Study of PI3Kα Inhibitor, RLY-5836, in Combination With Targeted and Endocrine Therapies in Participants With Advanced Breast Cancer and as a Single Agent in Advanced Solid Tumors

NCT05759949 is registered in ClinicalTrials.gov with Relay Therapeutics, Inc. as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A First-in-Human Study of PI3Kα Inhibitor, RLY-5836, in Combination With Targeted and Endocrine Therapies in Participants With Advanced Breast Cancer and as a Single Agent in Advanced Solid Tumors
Lead sponsor
Relay Therapeutics, Inc.
Phase
Phase 1
Overall status
Completed
Start date
March 29, 2023
Completion date
April 11, 2025
Enrollment
41 (actual)
Sites
7

Conditions

As the registry lists them; a condition with its own page is linked.

advanced breast cancer, breast cancer, her2-negative breast cancer, hormone receptor positive tumor, metastatic breast cancer, pik3ca mutation, solid tumor, adult, unresectable solid tumor