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Clinical trial

A Phase 2 Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, in Adults and Children With PIK3CA Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation

NCT06789913 is registered in ClinicalTrials.gov with Relay Therapeutics, Inc. as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase 2 Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, in Adults and Children With PIK3CA Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation
Lead sponsor
Relay Therapeutics, Inc.
Phase
Phase 2
Overall status
Recruiting
Start date
June 13, 2025
Completion date
October 31, 2031
Enrollment
277 (estimated)
Sites
40

Conditions

As the registry lists them; a condition with its own page is linked.

cloves syndrome, klippel trenaunay syndrome, lymphatic malformations, megalencephaly-capillary malformation polymicrogyria syndrome (mcap), pik3ca mutation, pik3ca-related overgrowth spectrum (pros), vascular anomalies, vascular malformations