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Clinical trial

Multicenter, Single-arm, 3 Cohort, Phase II Trial of HER3-DXd in Patients With Active Brain Metastases From Metastatic Breast Cancer and Non-small Cell Lung Cancer, and in Patients With Leptomeningeal Disease From Advanced Solid Tumors

NCT05865990 is registered in ClinicalTrials.gov with MedSIR as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
Multicenter, Single-arm, 3 Cohort, Phase II Trial of HER3-DXd in Patients With Active Brain Metastases From Metastatic Breast Cancer and Non-small Cell Lung Cancer, and in Patients With Leptomeningeal Disease From Advanced Solid Tumors
Lead sponsor
MedSIR
Phase
Phase 2
Overall status
Completed
Start date
November 24, 2023
Completion date
April 3, 2026
Enrollment
63 (actual)
Sites
8

Conditions

As the registry lists them; a condition with its own page is linked.

advanced non-small cell squamous lung cancer, metastatic breast cancer, solid tumor, adult