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Clinical trial

A Phase 1 Study Evaluating SC291, a Hypoimmune, Allogeneic CD19-directed CAR T Cell Therapy, in Subjects With Severe Relapsed or Refractory Autoimmune Diseases (GLEAM)

NCT06294236 is registered in ClinicalTrials.gov with Sana Biotechnology as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase 1 Study Evaluating SC291, a Hypoimmune, Allogeneic CD19-directed CAR T Cell Therapy, in Subjects With Severe Relapsed or Refractory Autoimmune Diseases (GLEAM)
Lead sponsor
Sana Biotechnology
Phase
Phase 1
Overall status
Active, not recruiting
Start date
April 29, 2024
Completion date
March 31, 2028
Enrollment
7 (estimated)
Sites
5

Conditions

As the registry lists them; a condition with its own page is linked.

anti-neutrophil cytoplasmic antibody-associated vasculitis, granulomatous polyangiitis, lupus erythematosus, microscopic polyangiitis, sle (systemic lupus), systemic lupus erythematosus