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Clinical trial

A Phase 1/2 Study Investigating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Antitumor Activity of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Selected Advanced or Metastatic Solid Tumors

NCT06427941 is registered in ClinicalTrials.gov with BeOne Medicines as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase 1/2 Study Investigating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Antitumor Activity of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Selected Advanced or Metastatic Solid Tumors
Lead sponsor
BeOne Medicines
Phase
Phase 1/2
Overall status
Recruiting
Start date
July 23, 2024
Completion date
October 31, 2028
Enrollment
630 (estimated)
Sites
51

Conditions

As the registry lists them; a condition with its own page is linked.

alpha-fetoprotein (afp)-producing gastric cancer, extragonadal yolk sac tumors, glypican-3 (gpc3)-positive squamous non-small cell lung cancer, local advanced hepatocellular carcinoma, metastatic hepatocellular carcinoma