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Clinical trial

DIRECT: Doxycycline Adjunctive Therapy to Reduce Excess Mortality and Complications From Central Nervous System Tuberculosis - Phase II Randomized Clinical Trial

NCT06446245 is registered in ClinicalTrials.gov with National University Hospital, Singapore as lead sponsor.

NCT NCT06446245
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Registry record

As filed in ClinicalTrials.gov.

Title
DIRECT: Doxycycline Adjunctive Therapy to Reduce Excess Mortality and Complications From Central Nervous System Tuberculosis - Phase II Randomized Clinical Trial
Lead sponsor
National University Hospital, Singapore
Phase
Phase 2
Overall status
Recruiting
Start date
August 21, 2025
Completion date
December 31, 2027
Enrollment
200 (estimated)
Sites
6

Conditions

As the registry lists them; a condition with its own page is linked.

tuberculosis, central nervous system, tuberculosis, meningeal, tuberculosis; meningitis (etiology), tuberculosis; meningoencephalitis (etiology)