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Clinical trial

A Phase I/IIa Study to Evaluate the Efficacy of DB107-RRV (Formerly Toca511), Administered to Subjects at Time of Resection and Intravenously Thereafter, in Combination With DB107-FC (Formerly Toca FC) and Radiation Therapy or DB107-FC, Temozolomide (TMZ) and Radiation Therapy in Patients With Newly Diagnosed High Grade Glioma

NCT06504381 is registered in ClinicalTrials.gov with University of California, San Francisco as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase I/IIa Study to Evaluate the Efficacy of DB107-RRV (Formerly Toca511), Administered to Subjects at Time of Resection and Intravenously Thereafter, in Combination With DB107-FC (Formerly Toca FC) and Radiation Therapy or DB107-FC, Temozolomide (TMZ) and Radiation Therapy in Patients With Newly Diagnosed High Grade Glioma
Lead sponsor
University of California, San Francisco
Phase
Phase 1/2
Overall status
Recruiting
Start date
January 8, 2025
Completion date
January 31, 2042
Enrollment
70 (estimated)
Sites
5

Conditions

As the registry lists them; a condition with its own page is linked.

high grade glioma, mgmt-methylated glioblastoma, mgmt-unmethylated glioblastoma