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Clinical trial

A Phase 1/2, Randomized, Double-blind, Placebo-controlled 2-part Study of the Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of Single Dose ALN-4324 in Overweight to Obese Adult Healthy Volunteers and Multiple Dose ALN-4324 in Overweight to Obese Patients With Type 2 Diabetes Mellitus (T2DM)

NCT06845202 is registered in ClinicalTrials.gov with Alnylam Pharmaceuticals as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase 1/2, Randomized, Double-blind, Placebo-controlled 2-part Study of the Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of Single Dose ALN-4324 in Overweight to Obese Adult Healthy Volunteers and Multiple Dose ALN-4324 in Overweight to Obese Patients With Type 2 Diabetes Mellitus (T2DM)
Lead sponsor
Alnylam Pharmaceuticals
Phase
Phase 1/2
Overall status
Active, not recruiting
Start date
March 3, 2025
Completion date
August 31, 2027
Enrollment
105 (actual)
Sites
22

Conditions

As the registry lists them; a condition with its own page is linked.

obese or overweight healthy volunteers, type 2 diabetes mellitus (t2dm)