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Clinical trial

A Pilot Study of Intrathecal Topotecan and Maintenance Chemotherapy in the Post-consolidation Setting for the Treatment of High-risk Embryonal Central Nervous System Tumours in Children Less Than 6 Years of Age

NCT06942039 is registered in ClinicalTrials.gov with C17 Council as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Pilot Study of Intrathecal Topotecan and Maintenance Chemotherapy in the Post-consolidation Setting for the Treatment of High-risk Embryonal Central Nervous System Tumours in Children Less Than 6 Years of Age
Lead sponsor
C17 Council
Phase
Phase 1
Overall status
Recruiting
Start date
September 23, 2025
Completion date
December 31, 2032
Enrollment
15 (estimated)
Sites
12

Conditions

As the registry lists them; a condition with its own page is linked.

atypical teratoid rhabdoid tumor, cns embryonal tumor, cns embryonal tumor with rhabdoid features, cns embryonal tumor, nos, cns, medulloblastoma, embryonal tumor with abundant neuropil and true rosettes, embryonal tumor with multilayered rosettes, ependymoblastoma, medulloblastoma, childhood, medulloblastoma, group 3, medulloblastoma, group 4, medulloepithelioma, neuroblastoma, pineoblastoma