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Condition (MeSH)

Rhabdoid Tumor

ClinicalTrials.gov lists 115 trials for Rhabdoid Tumor or a narrower condition beneath it. National Cancer Institute (NCI) has the most among industry and government lead sponsors, with 21.

MeSH D018335 Neoplasms Neoplasm C04 Listed by Orphanet as a rare disease
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Phase 1 Phase 1 55 Phase 1/2 Phase 1/2 8 Phase 2 Phase 2 30 Phase 3 Phase 3 3 Not applicable Not applicable 5 Observational Observational 12 Expanded access Expanded access 2 Phase 1 Phase 1 55 Phase 1/2 Phase 1/2 8 Phase 2 Phase 2 30 Phase 3 Phase 3 3 Not applicable Not applicable 5 Observational Observational 12 Expanded access Expanded access 2

Trials per phase (log scale)

115 of the 115 trials are tagged with Rhabdoid Tumor itself; the rest are tagged with a narrower condition beneath it.

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The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Rhabdoid Tumor trials start? (29)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 3
  • Not applicable
  • Observational

Top of scale: 10

1992: 1 trials (Observational 1) 1996: 1 trials (Phase 2 1) 1997: 1 trials (Phase 1 1) 1998: 2 trials (Phase 2 1, Phase 1 1) 2001: 1 trials (Observational 1) 2002: 3 trials (Phase 2 1, Phase 1 2) 2003: 2 trials (Phase 3 1, Phase 2 1) 2004: 5 trials (Observational 2, Phase 3 1, Phase 1 2) 2005: 6 trials (Not applicable 1, Phase 1 5) 2006: 3 trials (Observational 1, Phase 2 1, Phase 1 1) 2007: 2 trials (Observational 1, Phase 2 1) 2008: 2 trials (Phase 1/2 1, Phase 1 1) 2009: 2 trials (Phase 3 1, Phase 1 1) 2010: 3 trials (Not applicable 1, Phase 1 2) 2011: 4 trials (Observational 1, Not applicable 2, Phase 1 1) 2012: 3 trials (Observational 1, Phase 1 2) 2014: 2 trials (Not applicable 1, Phase 2 1) 2015: 3 trials (Phase 2 1, Phase 1 2) 2016: 4 trials (Phase 2 1, Phase 1 3) 2017: 10 trials (Observational 1, Phase 2 6, Phase 1/2 1, Phase 1 2) 2018: 7 trials (Phase 2 4, Phase 1 3) 2019: 7 trials (Phase 2 2, Phase 1 5) 2020: 9 trials (Observational 1, Phase 2 4, Phase 1/2 1, Phase 1 3) 2021: 6 trials (Phase 2 1, Phase 1/2 1, Phase 1 4) 2022: 3 trials (Phase 2 1, Phase 1/2 1, Phase 1 1) 2023: 4 trials (Observational 1, Phase 2 1, Phase 1/2 1, Phase 1 1) 2024: 4 trials (Phase 2 1, Phase 1 3) 2025: 4 trials (Phase 1 4)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 9
2025 4
2024 4
2023 4
2022 3
2021 6
2020 9
2019 7
2018 7
2017 10

No forecast is made for this condition: it averages 4.8 trial starts a year over the five years to September, under the 5 a year the method needs.

Prediction, not a registry value: median of 36 months from start to primary completion across 19 trials still running at the 2026-10-09 snapshot; registered median of 56 months across 77 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Rhabdoid Tumor trials in? (7)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 55
Phase 1/2 8
Phase 2 30
Phase 3 3
Not applicable 5
Observational 12
Expanded access 2

How many Rhabdoid Tumor trials are recruiting? (8)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 3
Recruiting 20
Active, not recruiting 22
Completed 47
Terminated 14

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Rhabdoid Tumor trials? (4)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Cancer Institute (NCI) 21
Pediatric Brain Tumor Consortium 9
Children's Oncology Group 8
Epizyme, Inc. 3

Which drugs are being tested for Rhabdoid Tumor? (3)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Cytoxan 15
Thiotepa 7
TOPOTECAN 6

Interventions as named in the registry (12)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Etoposid 14
or carboplatin 10
SOC: Temozolomide 10
Filgrastime (G-CSF) 9
Vincristina 8

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Rhabdoid Tumor trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Vomiting 24 10
Febrile neutropenia 22 4
Seizure 22 10
Disease progression 19 10
Respiratory failure 18 8

Which publications cover Rhabdoid Tumor? (18)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Delta-24-RGD, an Oncolytic Adenovirus, Increases Survival and Promotes Proinflammatory Immune Landscape Remodeling in Models of AT/RT and CNS-PNET. Clinical cancer research : an official journal of the American Association for Cancer Research 2021 Yes
Reply to S.A. Upadhyaya. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2020 Yes
A Phase I Study of the CDK4/6 Inhibitor Ribociclib (LEE011) in Pediatric Patients with Malignant Rhabdoid Tumors, Neuroblastoma, and Other Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Yes
Diagnostic value of next-generation sequencing in an unusual sphenoid tumor. The oncologist 2014 Yes
Synchronous perivesical and renal malignant rhabdoid tumor in a 9-year-old boy: a case report and review of literature. Urology 2013 Yes

Prevalence (9)

Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.

Prevalence
Orphanet disease Type Class Geography Jurisdiction Mapping relation
Rhabdoid tumor Annual incidence <1 / 1 000 000 Europe Not stated Exact
Rhabdoid tumor Point prevalence Unknown Worldwide Not stated Exact
Rhabdoid tumor Cases families Worldwide Not stated Exact
Rhabdoid tumor Annual incidence <1 / 1 000 000 Europe Not stated Exact
Rhabdoid tumor Point prevalence Unknown Worldwide Not stated Unspecified

Rare-disease identity (2)

Shown in this order: exact, broader, narrower, other.

Rare-disease identity
Orphanet disease ORPHA code Relation Source
Rhabdoid tumor 69077 Exact Orphadata Science knowledge files, Product 1
Rhabdoid tumor 69077 Exact Orphanet Rare Disease Ontology (ORDO)

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: sub-conditions in mesh.

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